Ronadip R Banerjee

Publication Details

  • Resistin: molecular history and prognosis JOURNAL OF MOLECULAR MEDICINE-JMM Banerjee, R. R., Lazar, M. A. 2003; 81 (4): 218-226

    Abstract:

    Obesity and diabetes have reached epidemic proportions worldwide. The antidiabetic thiazolidinedione (TZD) drugs are insulin-sensitizing agents now widely used in the treatment of type 2 diabetes. TZDs are ligands for the nuclear hormone receptor peroxisome proliferator activated receptor gamma, which is a master regulator of adipogenesis and adipocyte metabolism. The molecular mechanisms by which TZDs improve insulin sensitivity have not been fully identified. Here we consider a novel secreted factor first identified as a TZD-suppressible gene in mouse adipocytes, called resistin, and discuss what is currently known about resistin regulation and function in mouse and human.

    View details for DOI 10.1007/s00109-003-0428-9

    View details for Web of Science ID 000183629500002

    View details for PubMedID 12700889

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