Mark Holodniy

Publication Details

  • Successful management of disseminated Nocardia transvalensis infection in a heart transplant recipient after development of sulfonamide resistance: Case report and review JOURNAL OF HEART AND LUNG TRANSPLANTATION Lopez, F. A., Johnson, F., Novosad, D. M., Beaman, B. L., Holodniy, M. 2003; 22 (4): 492-497


    Nocardia transvalensis is a rarely reported cause of clinically significant disease, and, to our knowledge, has not been reported previously as a cause of infection in the cardiac transplant population. We report a case of N transvalensis new taxon-2 pulmonary infection that disseminated to the brain and skin in a cardiac transplant recipient despite adequate sulfonamide serum levels. Subsequent isolates were resistant to sulfonamides, and molecular ribotyping of the primary and subsequent isolates confirmed that these were the same N transvalensis new taxon-2 strain. The taxonomic and diagnostic considerations, as well as the clinical significance of anti-microbial-resistant nocardia, are reviewed and discussed herein.

    View details for DOI 10.1016/S1053-2498(02)00663-0

    View details for Web of Science ID 000182020300017

    View details for PubMedID 12681430

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