Lawrence Steinman

Publication Details

  • INVIVO THERAPY WITH MONOCLONAL ANTI-I-A ANTIBODY SUPPRESSES IMMUNE-RESPONSES TO ACETYLCHOLINE-RECEPTOR PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES Waldor, M. K., Sriram, S., McDevitt, H. O., Steinman, L. 1983; 80 (9): 2713-2717

    Abstract:

    A monoclonal antibody to I-A gene products of the immune response gene complex attenuates both humoral and cellular responses to acetylcholine receptor and appears to suppress clinical manifestations of experimental autoimmune myasthenia gravis. This demonstrates that use of antibodies against immune response gene products that are associated with susceptibility to disease may be feasible for therapy in autoimmune conditions such as myasthenia gravis.

    View details for Web of Science ID A1983QN81900063

    View details for PubMedID 6405386

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