Craig V. Comiter
Publication Details
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The effect of sildenafil citrate on bladder outlet obstruction: a mouse model.
BJU Int. 2009; (2): 252-6
To investigate if sildenafil citrate can inhibit the functional and structural changes of the detrusor in a murine model of bladder outlet obstruction (BOO). Phosphodiesterase type 5 (PDE-5) inhibitors have recently been used for treating urinary symptoms associated with prostatic obstruction, but it is unclear whether PDE-5 inhibition acts on the prostatic urethra or the bladder.
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