Daniel A. Arber, M.D.

Publication Details

  • Primary effusion lymphoma with subsequent development of a small bowel mass in an HIV-seropositive patient - A case report and literature review AMERICAN JOURNAL OF SURGICAL PATHOLOGY Huang, Q., Chang, K. L., Gaal, K., Arber, D. A. 2002; 26 (10): 1363-1367


    Primary effusion lymphoma is a distinct clinicopathologic entity usually characterized by presentation as a lymphomatous body cavity effusion in the absence of a solid tumor mass or dissemination during its clinical course. This lymphoma is typically present in human immunodeficiency virus (HIV)-infected patients and frequently associated with Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV8) viral sequences. Here we report a rare case of KSHV/HHV8-associated primary effusion lymphoma with secondary involvement of the small bowel as an obstructive tumor mass in an HIV-infected man. The solid small bowel lymphoma demonstrated essentially identical morphology, immunophenotype, KSHV/HHV8 viral status, and immunoglobulin light chain rearrangements to the pleural cavity-based primary effusion lymphoma in the same patient.

    View details for DOI 10.1097/01.PAS.0000027302.89469.AB

    View details for Web of Science ID 000178356400014

    View details for PubMedID 12360052

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