Brendan Carvalho
Publication Details
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The effect of OPRM1 and COMT genotypes on the analgesic response to intravenous fentanyl labor analgesia.
Anesth Analg. 2013; (2): 386-91
IV fentanyl is used as a labor analgesic; however, few studies have reported the effects of IV fentanyl for early labor analgesia. We evaluated the analgesic response to IV fentanyl according to the combined effect of the single-nucleotide polymorphisms rs1799971 (c.118A/G, p. 40Asn/Asp) of the ยต-opioid receptor gene (OPRM1) and rs4680 (c.472G/A, p.158Val/Met) of the catechol-O-methyltransferase (COMT) gene in women requesting labor analgesia.
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