Ann Weinacker
Publication Details
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Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation.
PLoS One. 2012; (12): e51932
Primary graft dysfunction (PGD) is a significant contributor to early morbidity and mortality after lung transplantation. Increased vascular permeability in the allograft has been identified as a possible mechanism leading to PGD. Angiopoietin-2 serves as a partial antagonist to the Tie-2 receptor and induces increased endothelial permeability. We hypothesized that elevated Ang2 levels would be associated with development of PGD.
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