Christy Sandborg

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Publication Details

  • Correlation analyses of clinical and molecular findings identify candidate biological pathways in systemic juvenile idiopathic arthritis.

    Ling XB, Macaubas C, Alexander HC, Wen Q, Chen E, Peng S, Sun Y, Deshpande C, Pan KH, Lin R, Lih CJ, Chang SY, Lee T, Sandborg C, Begovich AB, Cohen SN, Mellins ED. BMC Med. 2012: 10 125

    Clinicians have long appreciated the distinct phenotype of systemic juvenile idiopathic arthritis (SJIA) compared to polyarticular juvenile idiopathic arthritis (POLY). We hypothesized that gene expression profiles of peripheral blood mononuclear cells (PBMC) from children with each disease would reveal distinct biological pathways when analyzed for significant associations with elevations in two markers of JIA activity, erythrocyte sedimentation rate (ESR) and number of affected joints (joint count, JC).

    PubMedID: 23092393

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