David A. Relman

Publication Details

  • The search for unrecognized pathogens SCIENCE Relman, D. A. 1999; 284 (5418): 1308-1310

    Abstract:

    The distribution and diversity of microorganisms in the world are far greater than have been previously appreciated. Molecular, cultivation-independent methods have played a key role in this insight. To what extent do humans remain ignorant of microbial diversity within the human body and the settings in which microorganisms cause human disease? In addition to implicating microbial agents in nontraditional infectious diseases, the use of methods such as broad-range polymerase chain reaction, representational difference analysis, expression library screening, and host gene expression profiling may force a reassessment of the concepts of microbial disease causation.

    View details for Web of Science ID 000080430600040

    View details for PubMedID 10334977

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