Daniel Bernstein
Publication Details
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In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium.
Arterioscler Thromb Vasc Biol. 2012; (1): 92-102
Clinical trials of bone marrow-derived stem cell therapy for the heart have yielded variable results. The basic mechanism(s) that underlies their potential efficacy remains unknown. In the present study, we evaluated the survival kinetics, transcriptional response, and functional outcome of intramyocardial bone marrow mononuclear cell (BMMC) transplantation for cardiac repair in a murine myocardial infarction model.
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