Michael D. Dake

Publication Details

  • Superior vena cava syndrome: Treatment with catheter-directed thrombolysis and endovascular stent placement RADIOLOGY Kee, S. T., Kinoshita, L., Razavi, M. K., Nyman, U. R., Semba, C. P., Dake, M. D. 1998; 206 (1): 187-193

    Abstract:

    To evaluate use of catheter-directed thrombolysis and/or endovascular stent placement to treat superior vena cava (SVC) syndrome.Fifty-nine consecutive patients with SVC syndrome were studied. The cause was underlying malignancy in 43 and benign disease in 16. All patients underwent bilateral upper-extremity venography. The SVC was occluded in 31 cases and stenosed in 28. Twenty-seven patients underwent catheter-directed thrombolysis; 51 underwent endovascular stent placement. Patency was defined in terms of absence of symptoms and signs of SVC syndrome.Technical success was achieved in 56 of 59 patients (95%). Among 42 patients with underlying malignancy (mean follow-up, 7.0 months; range, 1-34 months), primary clinical patency was achieved in 33 (79%) and secondary clinical patency was achieved in 39 (93%). Among 13 patients with benign disease (mean follow-up, 17.0 months; range, 1-27 months), primary clinical patency was achieved in 10 (77%) and secondary clinical patency was achieved in 11 (85%). Four patients were lost to follow-up. Periprocedural mortality and morbidity rates were 3% (two of 59 patients) and 10% (six of 59 patients), respectively.Catheter-directed thrombolysis and endovascular stent placement is a safe and effective treatment for SVC syndrome.

    View details for Web of Science ID 000071093500034

    View details for PubMedID 9423671

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