Robert Herfkens

Publication Details

  • Measurement of vessel wall strain using cine phase contrast MRI Wedding, K. L., Draney, M. T., Herfkens, R. J., Zarins, C. K., Taylor, C. A., Pelc, N. J. JOHN WILEY & SONS INC. 2002: 418-428


    To determine the feasibility of using magnetic resonance imaging (MRI) to non-invasively measure strain in the aortic wall.Cine phase contrast MRI was used to measure the velocity of the aortic wall and calculate changes in circumferential strain over the cardiac cycle. A deformable vessel phantom was used for initial testing and in vitro validation. Ultrasonic sonomicrometer crystals were attached to the vessel wall and used as a gold standard.In the in vitro validation, MRI-calculated wall displacements were within 0.02 mm of the sonomicrometer measurements when maximal displacement was 0.28 mm. The measured maximum strain in vitro was 0.02. The in vivo results were on the same order as prior results using ultrasound echo-tracking.Results of in vivo studies and measurement of cyclic strain in human thoracic and abdominal aortas demonstrate the feasibility of the technique.

    View details for DOI 10.1002/jmri.10077

    View details for Web of Science ID 000174759700008

    View details for PubMedID 11948831

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