Peter Gregory

Publication Details

  • COMPLICATIONS OF DIURESIS IN ALCOHOLIC PATIENT WITH ASCITES - CONTROLLED TRIAL GASTROENTEROLOGY Gregory, P. B., BROEKELSCHEN, P. H., Hill, M. D., LIPTON, A. B., Knauer, C. M., Egger, M., Miller, R. 1977; 73 (3): 534-538

    Abstract:

    Forty-three patients with decompensated alcoholic liver disease and ascites of recent onset were randomized to salt and water restriction alone (control group) or to salt and water restriction plus diuretics (diuresis group). The two treatment groups were comparable in clinical findings and laboratory results. Seven patients in the control group and 5 patients in the diuresis group died during the acute illness. Weight loss was more marked and the disappearance of ascites more common in those given diuretics. A modest decrease in serum sodium and increase in serum potassium, and readily reversible elevations of blood urea nitrogen were noted in the diuresis group. Eight patients in each treatment group developed either the hepatorenal syndrome, marked electrolyte abnormalities, or encephalopathy. Diuresis can be accomplished in these critically ill patients without serious complications that can be attributed to the diuretic treatment.

    View details for Web of Science ID A1977DT01500019

    View details for PubMedID 892352

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