Frandics Chan

Publication Details

  • Computational fluid dynamic simulations of aortic coarctation comparing the effects of surgical- and stent-based treatments on aortic compliance and ventricular workload.

    Coogan JS, Chan FP, Taylor CA, Feinstein JA. Catheter Cardiovasc Interv. 2011; 77 (5): 680-91

    In this work, we examine the effects of stent-induced aortic stiffness on cardiac workload and blood pressure using computational fluid dynamic simulations. Background: Treatment of aortic coarctation (CoA) consists of either open, surgical repair or angioplasty with or without stenting. Although stenting is a minimally invasive alternative to surgery, aortic stiffness increases in the stented section. Concern over this increased stiffness has long been argued to be detrimental to the overall vascular health of the patient.

    PubMedID: 21061250

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