Robert Fisher

Publication Details

  • CLINICAL AND ELECTROENCEPHALOGRAPHIC EVIDENCE FOR SITES OF ORIGIN OF SEIZURES WITH DIFFUSE ELECTRODECREMENTAL PATTERN EPILEPSIA Arroyo, S., Lesser, R. P., Fisher, R. S., Vining, E. P., Krauss, G. L., BANDEENROCHE, K., Hart, J., GORDON, B., Uematsu, S., Webber, R. 1994; 35 (5): 974-987

    Abstract:

    A diffuse electrodecremental ictal pattern (DEP) has been associated with tonic seizures and, less often, with other forms of epilepsy and has been considered to reflect a generalized seizure disorder of diffuse cortical or subcortical (brainstem) origin. In some seizures associated with DEP, however, focal ictal manifestations have been observed. We reviewed the records of all patients admitted to our seizure monitoring unit for 3 years and detected 39 patients with seizures associated with DEP. In 23 of 39 patients, clinical ictal behaviors resembled seizures of unilateral supero/mesiofrontal lobe origin and interictal EEG showed a prominent unilateral frontal component. Nine of 39 had complex absences (CA)/complex partial seizures (CPS); 4 of them were of unilateral frontal lobe origin. Seven of 39 patients had tonic or atonic seizures. Seven patients were studied further with subdural electrodes. Ictal onsets showed a high-frequency frontal lobe discharge. We conclude that in a subgroup of patients a generalized electrodecremental pattern on scalp EEG results from a regional cortical high-frequency ictal discharge originating in a single frontal lobe.

    View details for Web of Science ID A1994PP61200010

    View details for PubMedID 7925169

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