Peter J. Koltai MD, FACS, FAAP

Publication Details

  • TREATMENT OF EXPERIMENTAL FROSTBITE WITH PENTOXIFYLLINE AND ALOE VERA CREAM ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY Miller, M. B., Koltai, P. J. 1995; 121 (6): 678-680

    Abstract:

    To compare the therapeutic effects of systemic pentoxifylline and topical aloe vera cream in the treatment of frostbite.The frostbitten ears of 10 New Zealand white rabbits were assigned to one of four treatment groups: untreated controls, those treated with aloe vera cream, those treated with pentoxifylline, and those treated with aloe vera cream and pentoxifylline.Tissue survival was calculated as the percent of total frostbite area that remained after 2 weeks.The control group had a 6% tissue survival. Tissue survival was notably improved with pentoxifylline (20%), better with aloe vera cream (24%), and the best with the combination therapy (30%).Pentoxifylline is as effective as aloe vera cream in improving tissue survival after frostbite injury.

    View details for Web of Science ID A1995RC17400015

    View details for PubMedID 7772322

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