James Chang
Publication Details
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Optimization of human tendon tissue engineering: synergistic effects of growth factors for use in tendon scaffold repopulation.
Plast Reconstr Surg. 2012; (2): 479-89
Tissue-engineered flexor tendon grafts may allow reconstruction of severe tendon losses. One critical factor is the optimization of cell proliferation and reseeding. Use of growth factors--basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF)-1, and platelet-derived growth factor (PDGF)-BB--may improve culture conditions for human fibroblasts, tenocytes, and adipose-derived stem cells and increase repopulation of a tendon scaffold.
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