Bertil Glader

Publication Details

  • MICROCYTOSIS ASSOCIATED WITH SICKLE-CELL ANEMIA AMERICAN JOURNAL OF CLINICAL PATHOLOGY Glader, B. E., PROPPER, R. D., Buchanan, G. R. 1979; 72 (1): 63-64

    Abstract:

    Sickle cell (Hb SS) anemia is considered a normochromic-normocytic hemolytic disorder. In 53 patients with Hb SS (mean reticulocyte values 16.8%), the authors observed that mean corpuscular hemoglobin (MCH) was 29.8 +/- 2.4 mu microgram and mean corpuscular hemoglobin (MCV) was 88.1 +/- 6.8 cu micrometers. In contrast, patients in a comparable hemolytic-disease group unrelated to hemoglobinopathies (mean reticulocyte count = 15.7%) had a higher MCH (33.0 +/- 1.8 mu microgram) and larger MCV (97 +/- 5.3 cu micrometers). These data indicate that Hb SS disease is associated with "relative microcytosis," presumably a consequence of reduced hemoglobin production.

    View details for Web of Science ID A1979HC87000011

    View details for PubMedID 453112

Stanford Medicine Resources:

Footer Links: