Darrell Wilson

Publication Details

  • PLASMA PRORENIN AND RENIN IN CHILDHOOD AND ADOLESCENCE AMERICAN JOURNAL OF DISEASES OF CHILDREN Wilson, D. M., Stevenson, D. K., LUETSCHER, J. A. 1988; 142 (10): 1070-1072

    Abstract:

    We studied 108 subjects (age range, 4 to 76 years) to determine the effect of age on prorenin (inactive renin), active renin, and plasma renin activity in normal children, adolescents, and adults. Children and adolescents had lower prorenin concentrations and higher plasma renin activity and active renin concentrations than did adults. Prorenin concentrations were positively correlated with age over the range of 4 to 76 years, while plasma renin activity and active renin concentration were negatively correlated with age. Plasma prorenin and active renin concentrations from umbilical cord blood samples obtained from 11 newborns and arterial samples obtained from five infants were higher than those in samples obtained from children or adults.

    View details for Web of Science ID A1988Q324900024

    View details for PubMedID 3052031

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