Waldo Concepcion

Publication Details

  • BABOON-TO-HUMAN CARDIAC XENOTRANSPLANTATION IN A NEONATE JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Bailey, L. L., NEHLSENCANNARELLA, S. L., Concepcion, W., JOLLEY, W. B. 1985; 254 (23): 3321-3329

    Abstract:

    This report details the first case of cardiac xenotransplantation in a neonate. The recipient, a victim of hypoplastic left heart syndrome (HLHS), survived 20 days. Autopsy findings are documented. The cardiac graft showed only traces of cell-mediated rejection. Graft failure appears to have resulted from a progressive, potentially avoidable humoral response, unmodified by immunosuppression. Cardiac allotransplantation and selective baboon-to-human xenotransplantation deserve further exploration as investigational therapy for neonatal HLHS.

    View details for Web of Science ID A1985AVW1000017

    View details for PubMedID 2933538

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