Gerald Reaven, MD

Publication Details

  • RELATIONSHIP BETWEEN GLUCOSE-TOLERANCE, INSULIN-SECRETION, AND INSULIN ACTION IN NON-OBESE INDIVIDUALS WITH VARYING DEGREES OF GLUCOSE-TOLERANCE DIABETOLOGIA Reaven, G. M., Hollenbeck, C. B., CHEN, Y. D. 1989; 32 (1): 52-55

    Abstract:

    Plasma glucose and insulin concentration following a 75 g oral glucose challenge and glucose uptake during a hyperinsulinaemic glucose clamp study were determined in 50 non-obese individuals. The study population was divided into five groups on the basis of their glucose tolerance: normal, impaired glucose tolerance, Type 2 (non-insulin-dependent) diabetes mellitus with fasting plasma glucose of less than 8 mmol/l, between 8-15 mmol/l, and more than 15 mmol/l. The plasma insulin response was significantly greater (p less than 0.001) than normal in those with either impaired glucose tolerance or Type 2 diabetes and a fasting plasma glucose concentration less than 8 mmol/l.(ABSTRACT TRUNCATED AT 250 WORDS)

    View details for Web of Science ID A1989T282000009

    View details for PubMedID 2651188

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