Christian Guilleminault

Publication Details

  • CAN AN ABNORMALITY OF CENTRAL NERVOUS-SYSTEM BE RESPONSIBLE FOR HEMODYNAMIC DISTURBANCES NOUVELLE PRESSE MEDICALE Guilleminault, C., Eldridge, F. L., Dement, W. 1975; 4 (18): 1343-1348

    Abstract:

    Twenty-seven subjects with insomnia or diurnal hypersomnolence presented a sleep apnea syndrome when their respiration was systematically checked during sleep. These sleep-induced respiratory abnormalities were completely occult and pulmonary function tests performed during wakefulness were normal. The patients, all non-obese, presented serious pulmonary artery pressure changes which were directly connected with the repetitive sleep apneas. Half of the patients also had systemic hypertension. Two children (aged 11 and 15) underwent tracheostomies which by-passed the sleep-induced obstruction. Systemic hypertension was reduced after surgery.

    View details for Web of Science ID A1975AA32300003

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