Michael S. B. Edwards

Publication Details

  • CRYPTIC VASCULAR MALFORMATIONS OF THE SPINAL-CORD - DIAGNOSIS BY MAGNETIC-RESONANCE-IMAGING AND OUTCOME OF SURGERY JOURNAL OF NEUROSURGERY Barnwell, S. L., Dowd, C. F., Davis, R. L., Edwards, M. S., Gutin, P. H., Wilson, C. B. 1990; 72 (3): 403-407

    Abstract:

    The cases of seven patients with intramedullary, cryptic vascular malformations of the spinal cord are reported. In all patients, the clinical course was progressive; a Brown-Séquard syndrome was the most common presenting symptom complex. Magnetic resonance (MR) imaging was performed in all patients. The pattern seen most often was a focus of high signal (on both T1- and T2-weighted MR images) surrounded by a larger zone of low signal (best seen on T2-weighted images), and was remarkably similar for all patients. Six patients underwent surgical exploration; removal of the lesions halted the progression of symptoms in five patients, and one patient had worsened sensory function after surgery. Motor function did not decrease postoperatively in any patient. The one patient who refused surgery has continued to decline neurologically. Histopathological examination of surgical specimens showed a cavernous malformation in one patient, a venous malformation in one, venous varices in two, and organizing hematomas in two; these findings are markedly different from those in previously reported cases of cryptic vascular malformations.

    View details for Web of Science ID A1990CP70900007

    View details for PubMedID 2303875

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