Valerie Chock

Publication Details

  • Variables Influencing Pregnancy Termination Following Prenatal Diagnosis of Fetal Chromosome Abnormalities JOURNAL OF GENETIC COUNSELING Hawkins, A., Stenzel, A., Taylor, J., Chock, V. Y., Hudgins, L. 2013; 22 (2): 238-248


    The objective of this study was to identify variables that may influence the decision to terminate or continue a pregnancy affected by a chromosome abnormality. We performed a retrospective cohort analysis of 286 pregnancies diagnosed with a chromosome abnormality following genetic counseling and prenatal diagnosis. Data obtained included procedure type, chromosome results, ethnicity, maternal age, use of fertility treatments, and uptake of genetic counseling after results, among other factors. Wilcoxon rank sum test, Fisher's exact test, and univariate and multivariate logistic regression models were used for data analysis. The overall termination rate in this study was 82.9 %. A lower likelihood to terminate was found in pregnancies with a diagnosis of a sex chromosome abnormality (OR 0.05, p?

    View details for DOI 10.1007/s10897-012-9539-1

    View details for Web of Science ID 000316291100008

    View details for PubMedID 23001505

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