David A. Relman

Publication Details

  • The meaning and impact of the human genome sequence for microbiology TRENDS IN MICROBIOLOGY Relman, D. A., FALKOW, S. 2001; 9 (5): 206-208


    The characterization of life is immeasurably enhanced by determination of complete genome sequences. For organisms that engage in intimate interactions with others, the genome sequence from one participant, and associated tools, provide unique insight into its partner. We discuss how the human genome sequence will further our understanding of microbial pathogens and commensals, and vice versa. We also propose criteria for implicating a host gene in microbial pathogenesis, and urge consideration of a'second human genome project'.

    View details for Web of Science ID 000168719300008

    View details for PubMedID 11336835

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