Randall Stafford

Publication Details

  • Enhancing Prescription Drug Innovation and Adoption ANNALS OF INTERNAL MEDICINE Alexander, G. C., O'Connor, A. B., Stafford, R. S. 2011; 154 (12): 833-U89

    Abstract:

    The adoption and use of a new drug would ideally be guided by its innovation and cost-effectiveness. However, information about the relative efficacy and safety of a drug is typically incomplete even well after market entry, and various other forces create a marketplace in which most new drugs are little better than their older counterparts. Five proposed mechanisms are considered for promoting innovation and reducing the use of therapies ultimately found to offer poor value or have unacceptable risks. These changes range from increasing the evidence required for U.S. Food and Drug Administration approval to modifying the structure of drug reimbursement. Despite the challenges of policy implementation, the United States has a long history of successfully improving the societal value and safe use of prescription medicines.

    View details for Web of Science ID 000291800500020

    View details for PubMedID 21690598

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