Euan A. Ashley

Publications

• APJ acts as a dual receptor in cardiac hypertrophy. Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P. Nature. 2012; 488 (7411): 394-8
• Cardiac structural and sarcomere genes associated with cardiomyopathy exhibit marked intolerance of genetic variation. Pan S, Caleshu CA, Dunn KE, Foti MJ, Moran MK, Soyinka O, Ashley EA. Circ Cardiovasc Genet. 2012; 5 (6): 602-10
• Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy. Chuan P, Sivaramakrishnan S, Ashley EA, Spudich JA. Biophys J. 2012; 102 (12): 2782-90
• DNA sequencing: clinical applications of new DNA sequencing technologies. Dewey FE, Pan S, Wheeler MT, Quake SR, Ashley EA. Circulation. 2012; 125 (7): 931-44
• Personal omics profiling reveals dynamic molecular and medical phenotypes. Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, Gallardo M, Blasco MA, Greenberg PL, Snyder P, Klein TE, Altman RB, Butte AJ, Ashley EA, Gerstein M, Nadeau KC, Tang H, Snyder M. Cell. 2012; 148 (6): 1293-307
• Gene coexpression network topology of cardiac development, hypertrophy, and failure. Dewey FE, Perez MV, Wheeler MT, Watt C, Spin J, Langfelder P, Horvath S, Hannenhalli S, Cappola TP, Ashley EA. Circ Cardiovasc Genet. 2011; 4 (1): 26-35
• Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA. PLoS Genet. 2011; 7 (9): e1002280
• Challenges in the clinical application of whole-genome sequencing. Ormond KE, Wheeler MT, Hudgins L, Klein TE, Butte AJ, Altman RB, Ashley EA, Greely HT. Lancet. 2010; 375 (9727): 1749-51
• Chromatin regulation by Brg1 underlies heart muscle development and disease. Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP. Nature. 2010; 466 (7302): 62-7
• Clinical assessment incorporating a personal genome. Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, Berlin DS, Thorn CF, Sangkuhl K, Hebert JM, Woon M, Sagreiya H, Whaley R, Knowles JW, Chou MF, Thakuria JV, Rosenbaum AM, Zaranek AW, Church GM, Greely HT, Quake SR, Altman RB. Lancet. 2010; 375 (9725): 1525-35
• A clinical approach to inherited hypertrophy: the use of family history in diagnosis, risk assessment, and management. Dunn KE, Caleshu C, Cirino AL, Ho CY, Ashley EA. Circ Cardiovasc Genet. 2013; 6 (1): 118-31
• Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC. Cell Stem Cell. 2013; 12 (1): 101-13
• Cardiopulmonary and noninvasive hemodynamic responses to exercise predict outcomes in heart failure. Myers J, Wong M, Adhikarla C, Boga M, Challa S, Abella J, Ashley EA. J Card Fail. 2013; 19 (2): 101-7
• Race Differences in Ventricular Remodeling and Function Among College Football Players. Haddad F, Peter S, Hulme O, Liang D, Schnittger I, Puryear J, Gomari FA, Finocchiaro G, Myers J, Froelicher V, Garza D, Ashley EA. Am J Cardiol. 2013
• Validation of a cardiopulmonary exercise test score in heart failure. Myers J, Oliveira R, Dewey F, Arena R, Guazzi M, Chase P, Bensimhon D, Peberdy MA, Ashley E, West E, Cahalin LP, Forman DE. Circ Heart Fail. 2013; 6 (2): 211-8
• Prognostic value of capnography during rest and exercise in patients with heart failure. Arena R, Guazzi M, Myers J, Chase P, Bensimhon D, Cahalin LP, Peberdy MA, Ashley E, West E, Forman DE. Congest Heart Fail. 2012 Nov-Dec; 18 (6): 302-7
• The prognostic utility of cardiopulmonary exercise testing stands the test of time in patients with heart failure. Arena R, Guazzi M, Myers J, Chase P, Bensimhon D, Cahalin LP, Peberdy MA, Ashley E, West E, Forman DE. J Cardiopulm Rehabil Prev. 2012 Jul-Aug; 32 (4): 198-202
• A public resource facilitating clinical use of genomes. Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. Proc Natl Acad Sci U S A. 2012; 109 (30): 11920-7
• Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells. Wang IN, Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC. PLoS One. 2012; 7 (6): e38328
• In situ optical mapping of voltage and calcium in the heart. Lee P, Taghavi F, Yan P, Ewart P, Ashley EA, Loew LM, Kohl P, Bollensdorff C, Woods CE. PLoS One. 2012; 7 (8): e42562
• Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sun N, Yazawa M, Liu J, Han L, Sanchez-Freire V, Abilez OJ, Navarrete EG, Hu S, Wang L, Lee A, Pavlovic A, Lin S, Chen R, Hajjar RJ, Snyder MP, Dolmetsch RE, Butte MJ, Ashley EA, Longaker MT, Robbins RC, Wu JC. Sci Transl Med. 2012; 4 (130): 130ra47
• Personalized medicine: hope or hype? Salari K, Watkins H, Ashley EA. Eur Heart J. 2012; 33 (13): 1564-70
• Prognostic implications of Q waves and T-wave inversion associated with early repolarization. Uberoi A, Sallam K, Perez M, Jain NA, Ashley E, Froelicher V. Mayo Clin Proc. 2012; 87 (7): 614-9
• Randomized trial of personal genomics for preventive cardiology: design and challenges. Knowles JW, Assimes TL, Kiernan M, Pavlovic A, Goldstein BA, Yank V, McConnell MV, Absher D, Bustamante C, Ashley EA, Ioannidis JP. Circ Cardiovasc Genet. 2012; 5 (3): 368-76
• Systems-based approaches to cardiovascular biomarker discovery. Azuaje FJ, Dewey FE, Brutsaert DL, Devaux Y, Ashley EA, Wagner DR. Circ Cardiovasc Genet. 2012; 5 (3): 360-7
• The prognostic value of early repolarization with ST-segment elevation in African Americans. Perez MV, Uberoi A, Jain NA, Ashley E, Turakhia MP, Froelicher V. Heart Rhythm. 2012; 9 (4): 558-65
• Ventilatory power: a novel index that enhances prognostic assessment of patients with heart failure. Forman DE, Guazzi M, Myers J, Chase P, Bensimhon D, Cahalin LP, Peberdy MA, Ashley E, West E, Daniels KM, Arena R. Circ Heart Fail. 2012; 5 (5): 621-6
• Whole-genome sequencing in personalized therapeutics. Cordero P, Ashley EA. Clin Pharmacol Ther. 2012; 91 (6): 1001-9
• Genetic analysis in cardiovascular disease: a clinical perspective. Ho E, Bhindi R, Ashley EA, Figtree GA. Cardiol Rev. 2011 Mar-Apr; 19 (2): 81-9
• BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. Perez VA, Ali Z, Alastalo TP, Ikeno F, Sawada H, Lai YJ, Kleisli T, Spiekerkoetter E, Qu X, Rubinos LH, Ashley E, Amieva M, Dedhar S, Rabinovitch M. J Cell Biol. 2011; 192 (1): 171-88
• Early repolarization in an ambulatory clinical population. Uberoi A, Jain NA, Perez M, Weinkopff A, Ashley E, Hadley D, Turakhia MP, Froelicher V. Circulation. 2011; 124 (20): 2208-14
• Exercise oscillatory ventilation reflects diminished quality of life and perceived functional capacity in patients with heart failure. Arena R, Guazzi M, Myers J, Chase P, Bensimhon D, Cahalin L, Peberdy MA, Ashley E, West E, Forman DE. Int J Cardiol. 2011; 153 (2): 213-4
• Hearts from DCD donors display acceptable biventricular function after heart transplantation in pigs. Ali AA, White P, Xiang B, Lin HY, Tsui SS, Ashley E, Lee TW, Klein JR, Kumar K, Arora RC, Large SR, Tian G, Freed DH. Am J Transplant. 2011; 11 (8): 1621-32
• Interpretation of the electrocardiogram of young athletes. Uberoi A, Stein R, Perez MV, Freeman J, Wheeler M, Dewey F, Peidro R, Hadley D, Drezner J, Sharma S, Pelliccia A, Corrado D, Niebauer J, Estes NA, Ashley E, Froelicher V. Circulation. 2011; 124 (6): 746-57
• Systems biology of heart failure, challenges and hopes. Dewey FE, Wheeler MT, Ashley EA. Curr Opin Cardiol. 2011; 26 (4): 314-21
• The concept of ventricular reserve in heart failure and pulmonary hypertension: an old metric that brings us one step closer in our quest for prediction. Haddad F, Vrtovec B, Ashley EA, Deschamps A, Haddad H, Denault AY. Curr Opin Cardiol. 2011; 26 (2): 123-31
• The impact of ST elevation on athletic screening. Leo T, Uberoi A, Jain NA, Garza D, Chowdhury S, Freeman JV, Perez M, Ashley E, Froelicher V. Clin J Sport Med. 2011; 21 (5): 433-40
• Addition of the electrocardiogram to the preparticipation examination of college athletes. Le VV, Wheeler MT, Mandic S, Dewey F, Fonda H, Perez M, Sungar G, Garza D, Ashley EA, Matheson G, Froelicher V. Clin J Sport Med. 2010; 20 (2): 98-105
• Cost-effectiveness of preparticipation screening for prevention of sudden cardiac death in young athletes. Wheeler MT, Heidenreich PA, Froelicher VF, Hlatky MA, Ashley EA. Ann Intern Med. 2010; 152 (5): 276-86
• Defining the limits of athlete's heart: implications for screening in diverse populations. Sedehi D, Ashley EA. Circulation. 2010; 121 (9): 1066-8
• Drug discovery in a multidimensional world: systems, patterns, and networks. Dudley JT, Schadt E, Sirota M, Butte AJ, Ashley E. J Cardiovasc Transl Res. 2010; 3 (5): 438-47
• Erratum: Insights into Human β-Cardiac Myosin Function from Single Molecule and Single Cell Studies. Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. J Cardiovasc Transl Res. 2010
• Measurement precision in the optimization of cardiac resynchronization therapy. Turcott RG, Witteles RM, Wang PJ, Vagelos RH, Fowler MB, Ashley EA. Circ Heart Fail. 2010; 3 (3): 395-404
• New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy. Haddad F, Ashley E, Michelakis ED. Curr Opin Cardiol. 2010; 25 (2): 131-40
• Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse. Kojima Y, Kundu RK, Cox CM, Leeper NJ, Anderson JA, Chun HJ, Ali ZA, Ashley EA, Krieg PA, Quertermous T. Cardiovasc Res. 2010; 87 (1): 156-65
• The medical device safety act of 2009: clarifying preemption. Turcott RG, Ashley EA. Am J Ther. 2009 Nov-Dec; 16 (6): 471-4
• A general framework for dose optimization. Turcott RG, Sagreiya H, Ashley EA, Altman RB, Das AK. AMIA Annu Symp Proc. 2009: 2009 656-60
• A new era in clinical genetic testing for hypertrophic cardiomyopathy. Wheeler M, Pavlovic A, DeGoma E, Salisbury H, Brown C, Ashley EA. J Cardiovasc Transl Res. 2009; 2 (4): 381-91
• Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T. Am J Physiol Heart Circ Physiol. 2009; 296 (5): H1329-35
• Electrocardiographic predictors of atrial fibrillation. Perez MV, Dewey FE, Marcus R, Ashley EA, Al-Ahmad AA, Wang PJ, Froelicher VF. Am Heart J. 2009; 158 (4): 622-8
• Endogenous regulation of cardiovascular function by apelin-APJ. Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T. Am J Physiol Heart Circ Physiol. 2009; 297 (5): H1904-13
• Insights into human beta-cardiac myosin function from single molecule and single cell studies. Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. J Cardiovasc Transl Res. 2009; 2 (4): 426-40
• Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy. Le VV, Perez MV, Wheeler MT, Myers J, Schnittger I, Ashley EA. Am Heart J. 2009; 158 (3): e27-34
• Re: A prospective randomized evaluation of VV delay optimization in CRT-D recipients: echocardiographic observations from the RHYTHM II ICD study. Turcott RG, Das AK, Ashley EA. Pacing Clin Electrophysiol. 2009; 32 (10): 1360-1; author reply 1361-2
• Should the exercise ECG be used to screen for sudden cardiac death? Freeman J, Ashley EA, Froelicher V. Eur Heart J. 2009; 30 (5): 528-9
• Statin use and ventricular arrhythmias during clinical treadmill testing. Dewey FE, Perez M, Hadley D, Freeman JV, Wang P, Ashley EA, Myers J, Froelicher VF. J Cardiovasc Electrophysiol. 2009; 20 (2): 193-9
• The ageing athlete: screening prior to vigorous exertion in asymptomatic adults without known cardiovascular disease. Freeman J, Froelicher V, Ashley E. Br J Sports Med. 2009; 43 (9): 696-701
• Age and double product (systolic blood pressure x heart rate) reserve-adjusted modification of the Duke Treadmill Score nomogram in men. Sadrzadeh Rafie AH, Dewey FE, Sungar GW, Ashley EA, Hadley D, Myers J, Froelicher VF. Am J Cardiol. 2008; 102 (10): 1407-12
• Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. J Clin Invest. 2008; 118 (10): 3343-54
• Does size matter? Clinical applications of scaling cardiac size and function for body size. Dewey FE, Rosenthal D, Murphy DJ, Froelicher VF, Ashley EA. Circulation. 2008; 117 (17): 2279-87
• Genetics of arrhythmia: disease pathways beyond ion channels. Perez MV, Wheeler M, Ho M, Pavlovic A, Wang P, Ashley EA. J Cardiovasc Transl Res. 2008; 1 (2): 155-65
• Low-dose growth hormone is cardioprotective in uremia. Rabkin R, Awwad I, Chen Y, Ashley EA, Sun D, Sood S, Clusin W, Heidenreich P, Piecha G, Gross ML. J Am Soc Nephrol. 2008; 19 (9): 1774-83
• Pharmacogenetics of heart failure: evidence, opportunities, and challenges for cardiovascular pharmacogenomics. Wheeler MT, Ho M, Knowles JW, Pavlovic A, Ashley EA. J Cardiovasc Transl Res. 2008; 1 (1): 25-36
• Progressive Dyspnea After CABG: Complication of Retained Epicardial Pacing Wires. Horng GS, Ashley E, Balsam L, Reitz B, Zamanian RT. Ann Thorac Surg. 2008; 86 (4): 1352-4
• Ventricular arrhythmias during clinical treadmill testing and prognosis. Dewey FE, Kapoor JR, Williams RS, Lipinski MJ, Ashley EA, Hadley D, Myers J, Froelicher VF. Arch Intern Med. 2008; 168 (2): 225-34
• Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis. Ashley EA, Spin JM, Tabibiazar R, Quertermous T. J Am Soc Nephrol. 2007; 18 (11): 2853-62
• Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse. Yue P, Arai T, Terashima M, Sheikh AY, Cao F, Charo D, Hoyt G, Robbins RC, Ashley EA, Wu J, Yang PC, Tsao PS. Am J Physiol Heart Circ Physiol. 2007; 292 (5): H2106-18
• Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease. Hlatky MA, Ashley E, Quertermous T, Boothroyd DB, Ridker P, Southwick A, Myers RM, Iribarren C, Fortmann SP, Go AS. Am Heart J. 2007; 154 (6): 1043-51
• Prognostic value of heart rate increase at onset of exercise testing. Leeper NJ, Dewey FE, Ashley EA, Sandri M, Tan SY, Hadley D, Myers J, Froelicher V. Circulation. 2007; 115 (4): 468-74
• Angiotensin-converting enzyme genotype predicts cardiac and autonomic responses to prolonged exercise. Ashley EA, Kardos A, Jack ES, Habenbacher W, Wheeler M, Kim YM, Froning J, Myers J, Whyte G, Froelicher V, Douglas P. J Am Coll Cardiol. 2006; 48 (3): 523-31
• Emerging therapies for the management of decompensated heart failure: from bench to bedside. deGoma EM, Vagelos RH, Fowler MB, Ashley EA. J Am Coll Cardiol. 2006; 48 (12): 2397-409
• Network analysis of human in-stent restenosis. Ashley EA, Ferrara R, King JY, Vailaya A, Kuchinsky A, He X, Byers B, Gerckens U, Oblin S, Tsalenko A, Soito A, Spin JM, Tabibiazar R, Connolly AJ, Simpson JB, Grube E, Quertermous T. Circulation. 2006; 114 (24): 2644-54
• Opposing cardiovascular roles for the angiotensin and apelin signaling pathways. Ashley E, Chun HJ, Quertermous T. J Mol Cell Cardiol. 2006; 41 (5): 778-81
• Perioperative cardiac risk: pathophysiology, assessment and management. Sista RR, Ernst KV, Ashley EA. Expert Rev Cardiovasc Ther. 2006; 4 (5): 731-43
• Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure. Chong KS, Gardner RS, Morton JJ, Ashley EA, McDonagh TA. Eur J Heart Fail. 2006; 8 (4): 355-60
• Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease. Tabibiazar R, Wagner RA, Spin JM, Ashley EA, Narasimhan B, Rubin EM, Efron B, Tsao PS, Tibshirani R, Quertermous T. Arterioscler Thromb Vasc Biol. 2005; 25 (2): 302-8
• Pathway analysis of coronary atherosclerosis. King JY, Ferrara R, Tabibiazar R, Spin JM, Chen MM, Kuchinsky A, Vailaya A, Kincaid R, Tsalenko A, Deng DX, Connolly A, Zhang P, Yang E, Watt C, Yakhini Z, Ben-Dor A, Adler A, Bruhn L, Tsao P, Quertermous T, Ashley EA. Physiol Genomics. 2005; 23 (1): 103-18
• Preoperative cardiac evaluation: mechanisms, assessment, and reduction of risk. Ashley EA, Vagelos RH. Thorac Surg Clin. 2005; 15 (2): 263-75
• Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease. Tabibiazar R, Wagner RA, Ashley EA, King JY, Ferrara R, Spin JM, Sanan DA, Narasimhan B, Tibshirani R, Tsao PS, Efron B, Quertermous T. Physiol Genomics. 2005; 22 (2): 213-26
• The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T. Cardiovasc Res. 2005; 65 (1): 73-82
• Electrocardiographic arrhythmia risk testing. Engel G, Beckerman JG, Froelicher VF, Yamazaki T, Chen HA, Richardson K, McAuley RJ, Ashley EA, Chun S, Wang PJ. Curr Probl Cardiol. 2004; 29 (7): 365-432
• Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component? Sears CE, Ashley EA, Casadei B. Philos Trans R Soc Lond B Biol Sci. 2004; 359 (1446): 1021-44
• Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation. Spin JM, Nallamshetty S, Tabibiazar R, Ashley EA, King JY, Chen M, Tsao PS, Quertermous T. Physiol Genomics. 2004; 19 (3): 292-302
• Cardiology Explained Ashley, Euan, Niebauer, Josef. Cardiology Explained. 2004: ISBN: 1901346226
• Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling. Sears CE, Bryant SM, Ashley EA, Lygate CA, Rakovic S, Wallis HL, Neubauer S, Terrar DA, Casadei B. Circ Res. 2003; 92 (5): e52-9
• Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Chen MM, Ashley EA, Deng DX, Tsalenko A, Deng A, Tabibiazar R, Ben-Dor A, Fenster B, Yang E, King JY, Fowler M, Robbins R, Johnson FL, Bruhn L, McDonagh T, Dargie H, Yakhini Z, Tsao PS, Quertermous T. Circulation. 2003; 108 (12): 1432-9
• Diagnosing coronary artery disease in diabetic patients. Ashley EA, Raxwal V, Finlay M, Froelicher V. Diabetes Metab Res Rev. 2002 May-Jun; 18 (3): 201-8
• Better decisions through science: exercise testing scores. Froelicher V, Shetler K, Ashley E. Prog Cardiovasc Dis. 2002 Mar-Apr; 44 (5): 395-414
• Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes. Ashley EA, Sears CE, Bryant SM, Watkins HC, Casadei B. Circulation. 2002; 105 (25): 3011-6
• Exercise testing scores as an example of better decisions through science. Ashley E, Myers J, Froelicher V. Med Sci Sports Exerc. 2002; 34 (8): 1391-8
• An evidence-based review of the resting electrocardiogram as a screening technique for heart disease. Ashley EA, Raxwal V, Froelicher V. Prog Cardiovasc Dis. 2001 Jul-Aug; 44 (1): 55-67
• Sex, the heart, and sildenafil. Alloggiamento T, Zipp C, Raxwal VK, Ashley E, Dey S, Levine S, Froelicher VF. Curr Probl Cardiol. 2001; 26 (6): 388-415
• The post myocardial infarction exercise test: still worthy after all of these years. Ashley EA, Froelicher V. Eur Heart J. 2001; 22 (4): 273-6
• Computer applications in the interpretation of the exercise electrocardiogram. Ashley EA, Froelicher VF. Sports Med. 2000; 30 (4): 231-48
• Exercise testing in clinical medicine. Ashley EA, Myers J, Froelicher V. Lancet. 2000; 356 (9241): 1592-7
• Medical education - beyond tomorrow? The new doctor - Asclepiad or Logiatros? Ashley EA, Med Educ. 2000; 34 (6): 455-9
• The prevalence and prognostic significance of electrocardiographic abnormalities. Ashley EA, Raxwal VK, Froelicher VF. Curr Probl Cardiol. 2000; 25 (1): 1-72
• Dangerous curves. A perspective on exercise, lactate, and the anaerobic threshold. Myers J, Ashley E. Chest. 1997; 111 (3): 787-95
• Hormonal responses to graded-resistance, FES-assisted strength training in spinal cord-injured. Wheeler GD, Ashley EA, Harber V, Laskin JJ, Olenik LM, Sloley D, Burnham R, Steadward RD, Cumming DC. Spinal Cord. 1996; 34 (5): 264-7
• Electrical stimulation-assisted rowing exercise in spinal cord injured people. A pilot study. Laskin JJ, Ashley EA, Olenik LM, Burnham R, Cumming DC, Steadward RD, Wheeler GD. Paraplegia. 1993; 31 (8): 534-41
• Evidence of autonomic dysreflexia during functional electrical stimulation in individuals with spinal cord injuries. Ashley EA, Laskin JJ, Olenik LM, Burnham R, Steadward RD, Cumming DC, Wheeler GD. Paraplegia. 1993; 31 (9): 593-605