Michael F. Clarke, M.D.

Publications

• MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Bockhorn J, Dalton R, Nwachukwu C, Huang S, Prat A, Yee K, Chang YF, Huo D, Wen Y, Swanson KE, Qiu T, Lu J, Park SY, Dolan ME, Perou CM, Olopade OI, Clarke MF, Greene GL, Liu H. Nat Commun. 2013: 4 1393
• Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice. Rothenberg ME, Nusse Y, Kalisky T, Lee JJ, Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, Beachy PA, Pasricha PJ, Quake SR, Clarke MF. Gastroenterology. 2012; 142 (5): 1195-1205.e6
• Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution. Sen A, Rothenberg ME, Mukherjee G, Feng N, Kalisky T, Nair N, Johnstone IM, Clarke MF, Greenberg HB. Proc Natl Acad Sci U S A. 2012; 109 (50): 20667-72
• Remodeling of endogenous mammary epithelium by breast cancer stem cells. Parashurama N, Lobo NA, Ito K, Mosley AR, Habte FG, Zabala M, Smith BR, Lam J, Weissman IL, Clarke MF, Gambhir SS. Stem Cells. 2012; 30 (10): 2114-27
• Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. Kohrt HE, Houot R, Weiskopf K, Goldstein MJ, Scheeren F, Czerwinski D, Colevas AD, Weng WK, Clarke MF, Carlson RW, Stockdale FE, Mollick JA, Chen L, Levy R. J Clin Invest. 2012; 122 (3): 1066-75
• The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PØ, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. Proc Natl Acad Sci U S A. 2012; 109 (17): 6662-7
• Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting. Liu H, Bockhorn J, Dalton R, Chang YF, Qian D, Zitzow LA, Clarke MF, Greene GL. J Virol Methods. 2011; 173 (2): 266-70
• Single-cell dissection of transcriptional heterogeneity in human colon tumors. Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR. Nat Biotechnol. 2011; 29 (12): 1120-7
• Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Liu H, Patel MR, Prescher JA, Patsialou A, Qian D, Lin J, Wen S, Chang YF, Bachmann MH, Shimono Y, Dalerba P, Adorno M, Lobo N, Bueno J, Dirbas FM, Goswami S, Somlo G, Condeelis J, Contag CH, Gambhir SS, Clarke MF. Proc Natl Acad Sci U S A. 2010; 107 (42): 18115-20
• The Myc connection: ES cells and cancer. Rothenberg ME, Clarke MF, Diehn M. Cell. 2010; 143 (2): 184-6
• Association of reactive oxygen species levels and radioresistance in cancer stem cells. Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF. Nature. 2009; 458 (7239): 780-3
• Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Wu AR, Hiatt JB, Lu R, Attema JL, Lobo NA, Weissman IL, Clarke MF, Quake SR. Lab Chip. 2009; 9 (10): 1365-70
• DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Hoey T, Yen WC, Axelrod F, Basi J, Donigian L, Dylla S, Fitch-Bruhns M, Lazetic S, Park IK, Sato A, Satyal S, Wang X, Clarke MF, Lewicki J, Gurney A. Cell Stem Cell. 2009; 5 (2): 168-77
• Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, Diehn M, Liu H, Panula SP, Chiao E, Dirbas FM, Somlo G, Pera RA, Lao K, Clarke MF. Cell. 2009; 138 (3): 592-603
• Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Majeti R, Becker MW, Tian Q, Lee TL, Yan X, Liu R, Chiang JH, Hood L, Clarke MF, Weissman IL. Proc Natl Acad Sci U S A. 2009; 106 (9): 3396-401
• Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials. Woodward WA, Bristow RG, Clarke MF, Coppes RP, Cristofanilli M, Duda DG, Fike JR, Hambardzumyan D, Hill RP, Jordan CT, Milas L, Pajonk F, Curran WJ, Dicker AP, Chen Y. Int J Radiat Oncol Biol Phys. 2009; 74 (5): 1580-91
• Therapeutic implications of the cancer stem cell hypothesis. Diehn M, Cho RW, Clarke MF. Semin Radiat Oncol. 2009; 19 (2): 78-86
• Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. Dylla SJ, Beviglia L, Park IK, Chartier C, Raval J, Ngan L, Pickell K, Aguilar J, Lazetic S, Smith-Berdan S, Clarke MF, Hoey T, Lewicki J, Gurney AL. PLoS One. 2008; 3 (6): e2428
• Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors. Cho RW, Wang X, Diehn M, Shedden K, Chen GY, Sherlock G, Gurney A, Lewicki J, Clarke MF. Stem Cells. 2008; 26 (2): 364-71
• Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors. Akala OO, Park IK, Qian D, Pihalja M, Becker MW, Clarke MF. Nature. 2008; 453 (7192): 228-32
• Recent advances in cancer stem cells. Cho RW, Clarke MF. Curr Opin Genet Dev. 2008; 18 (1): 48-53
• What can we learn about breast cancer from stem cells? Clarke MF, Adv Exp Med Biol. 2008: 617 17-22
• Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells. Hosen N, Yamane T, Muijtjens M, Pham K, Clarke MF, Weissman IL. Stem Cells. 2007; 25 (7): 1635-44
• Cancer stem cells and tumor metastasis: first steps into uncharted territory. Dalerba P, Clarke MF. Cell Stem Cell. 2007; 1 (3): 241-2
• Cancer stem cells: models and concepts. Dalerba P, Cho RW, Clarke MF. Annu Rev Med. 2007: 58 267-84
• Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. Liu TX, Becker MW, Jelinek J, Wu WS, Deng M, Mikhalkevich N, Hsu K, Bloomfield CD, Stone RM, DeAngelo DJ, Galinsky IA, Issa JP, Clarke MF, Look AT. Nat Med. 2007; 13 (1): 78-83
• Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P, Weissman IL, Clarke MF, Ailles LE. Proc Natl Acad Sci U S A. 2007; 104 (3): 973-8
• Identification of pancreatic cancer stem cells. Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM. Cancer Res. 2007; 67 (3): 1030-7
• Phenotypic characterization of human colorectal cancer stem cells. Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF. Proc Natl Acad Sci U S A. 2007; 104 (24): 10158-63
• The biology of cancer stem cells. Lobo NA, Shimono Y, Qian D, Clarke MF. Annu Rev Cell Dev Biol. 2007: 23 675-99
• The prognostic role of a gene signature from tumorigenic breast-cancer cells. Liu R, Wang X, Chen GY, Dalerba P, Gurney A, Hoey T, Sherlock G, Lewicki J, Shedden K, Clarke MF. N Engl J Med. 2007; 356 (3): 217-26
• Cancer stem cells and radiotherapy: new insights into tumor radioresistance. Diehn M, Clarke MF. J Natl Cancer Inst. 2006; 98 (24): 1755-7
• Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH, Jones DL, Visvader J, Weissman IL, Wahl GM. Cancer Res. 2006; 66 (19): 9339-44
• Hematopoietic stem cell self-renewal. Akala OO, Clarke MF. Curr Opin Genet Dev. 2006; 16 (5): 496-501
• Oncogenes, self-renewal and cancer. Clarke MF, Pathol Biol (Paris). 2006; 54 (2): 109-11
• Stem cells and cancer: two faces of eve. Clarke MF, Fuller M. Cell. 2006; 124 (6): 1111-5
• Stem cells: the real culprits in cancer? Clarke MF, Becker MW. Sci Am. 2006; 295 (1): 52-9
• A self-renewal assay for cancer stem cells. Clarke MF, Cancer Chemother Pharmacol. 2005: 56 Suppl 1 64-8
• Epigenetic regulation of normal and cancer stem cells. Clarke MF, Ann N Y Acad Sci. 2005: 1044 90-3
• Self-renewal and solid-tumor stem cells. Clarke MF, Biol Blood Marrow Transplant. 2005; 11 (2 Suppl 2): 14-6
• Bmi1, stem cells, and senescence regulation. Park IK, Morrison SJ, Clarke MF. J Clin Invest. 2004; 113 (2): 175-9
• Chronic myelogenous leukemia--identifying the hydra's heads. Clarke MF, N Engl J Med. 2004; 351 (7): 634-6
• Neurobiology: at the root of brain cancer. Clarke MF, Nature. 2004; 432 (7015): 281-2
• Self-renewal and solid tumor stem cells. Al-Hajj M, Clarke MF. Oncogene. 2004; 23 (43): 7274-82
• Therapeutic implications of cancer stem cells. Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF. Curr Opin Genet Dev. 2004; 14 (1): 43-7
• Applying the principles of stem-cell biology to cancer. Pardal R, Clarke MF, Morrison SJ. Nat Rev Cancer. 2003; 3 (12): 895-902
• Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Nature. 2003; 425 (6961): 962-7
• Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL, Morrison SJ, Clarke MF. Nature. 2003; 423 (6937): 302-5
• In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, Wicha MS. Genes Dev. 2003; 17 (10): 1253-70
• Prospective identification of tumorigenic breast cancer cells. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Proc Natl Acad Sci U S A. 2003; 100 (7): 3983-8
• Stem cells in normal breast development and breast cancer. Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS. Cell Prolif. 2003: 36 Suppl 1 59-72
• A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. Morrison SJ, Qian D, Jerabek L, Thiel BA, Park IK, Ford PS, Kiel MJ, Schork NJ, Weissman IL, Clarke MF. J Immunol. 2002; 168 (2): 635-42
• Differential gene expression profiling of adult murine hematopoietic stem cells. Park IK, He Y, Lin F, Laerum OD, Tian Q, Bumgarner R, Klug CA, Li K, Kuhr C, Doyle MJ, Xie T, Schummer M, Sun Y, Goldsmith A, Clarke MF, Weissman IL, Hood L, Li L. Blood. 2002; 99 (2): 488-98
• New oncolytic adenoviruses with hypoxia- and estrogen receptor-regulated replication. Hernandez-Alcoceba R, Pihalja M, Qian D, Clarke MF. Hum Gene Ther. 2002; 13 (14): 1737-50
• SLUGging away at cell death. Becker MW, Clarke MF. Cancer Cell. 2002; 2 (4): 249-51
• Clinical protocol. Purging of autologous stem cell sources with bcl-x(s) adenovirus for women undergoing high-dose chemotherapy for stage IV breast carcinoma. Ayash LJ, Clarke M, Adams P, Ferrara J, Ratanatharathorn V, Reynolds C, Roessler B, Silver S, Strawderman M, Uberti J, Wicha M. Hum Gene Ther. 2001; 12 (16): 2023-5
• Double dose-intensive chemotherapy with autologous stem cell support for relapsed and refractory testicular cancer: the University of Michigan experience and literature review. Ayash LJ, Clarke M, Silver SM, Braun T, Uberti J, Ratanatharathorn V, Reynolds C, Ferrara J, Broun ER, Adams PT. Bone Marrow Transplant. 2001; 27 (9): 939-47
• Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells. Hernandez-Alcoceba R, Pihalja M, Nunez G, Clarke MF. Cancer Gene Ther. 2001; 8 (4): 298-307
• Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells. Park IK, Klug CA, Li K, Jerabek L, Li L, Nanamori M, Neubig RR, Hood L, Weissman IL, Clarke MF. J Biol Chem. 2001; 276 (2): 915-23
• Regulation of p53 localization. Liang SH, Clarke MF. Eur J Biochem. 2001; 268 (10): 2779-83
• Stem cells, cancer, and cancer stem cells. Reya T, Morrison SJ, Clarke MF, Weissman IL. Nature. 2001; 414 (6859): 105-11
• A novel, conditionally replicative adenovirus for the treatment of breast cancer that allows controlled replication of E1a-deleted adenoviral vectors. Hernandez-Alcoceba R, Pihalja M, Wicha MS, Clarke MF. Hum Gene Ther. 2000; 11 (14): 2009-24
• A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain. Liang SH, Clarke MF. J Biol Chem. 1999; 274 (46): 32699-703
• Germ cell tumor: differentiation of viable tumor, mature teratoma, and necrotic tissue with FDG PET and kinetic modeling. Sugawara Y, Zasadny KR, Grossman HB, Francis IR, Clarke MF, Wahl RL. Radiology. 1999; 211 (1): 249-56
• The nuclear import of p53 is determined by the presence of a basic domain and its relative position to the nuclear localization signal. Liang SH, Clarke MF. Oncogene. 1999; 18 (12): 2163-6
• A method of limited replication for the efficient in vivo delivery of adenovirus to cancer cells. Han JS, Qian D, Wicha MS, Clarke MF. Hum Gene Ther. 1998; 9 (8): 1209-16
• Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein. Liang SH, Hong D, Clarke MF. J Biol Chem. 1998; 273 (31): 19817-21
• Role of p53 in the regulation of irradiation-induced apoptosis in neuroblastoma cells. Jasty R, Lu J, Irwin T, Suchard S, Clarke MF, Castle VP. Mol Genet Metab. 1998; 65 (2): 155-64
• Targeting cancer cell death with a bcl-XS adenovirus. Han JS, Núñez G, Wicha MS, Clarke MF. Springer Semin Immunopathol. 1998; 19 (3): 279-88
• Prevention of fluorodeoxyuridine-induced cytotoxicity and DNA damage in HT29 colon carcinoma cells by conditional expression of wild-type p53 phenotype. Parsels LA, Zellars RC, Loney TL, Parsels JD, Clarke MF, Merchant AK, Lawrence TS, Maybaum J. Mol Pharmacol. 1997; 52 (4): 600-5
• Bcl-xS enhances adenoviral vector-induced apoptosis in neuroblastoma cells. Dole MG, Clarke MF, Holman P, Benedict M, Lu J, Jasty R, Eipers P, Thompson CB, Rode C, Bloch C, Nuñez, Castle VP. Cancer Res. 1996; 56 (24): 5734-40
• Retroviral infection is limited by Brownian motion. Chuck AS, Clarke MF, Palsson BO. Hum Gene Ther. 1996; 7 (13): 1527-34
• bcl-xs gene therapy induces apoptosis of human mammary tumors in nude mice. Ealovega MW, McGinnis PK, Sumantran VN, Clarke MF, Wicha MS. Cancer Res. 1996; 56 (9): 1965-9
• A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells. Clarke MF, Apel IJ, Benedict MA, Eipers PG, Sumantran V, González-García M, Doedens M, Fukunaga N, Davidson B, Dick JE, Minn AJ, Boise LH, Thompson CB, Wicha M, Núñez G. Proc Natl Acad Sci U S A. 1995; 92 (24): 11024-8
• Bcl-2 protects murine erythroleukemia cells from p53-dependent and -independent radiation-induced cell death. Fukunaga-Johnson N, Ryan JJ, Wicha M, Nuñez G, Clarke MF. Carcinogenesis. 1995; 16 (8): 1761-7
• Bcl-XL protects cancer cells from p53-mediated apoptosis. Schott AF, Apel IJ, Nuñez G, Clarke MF. Oncogene. 1995; 11 (7): 1389-94
• In vitro expansion of hematopoietic cells for clinical application. Emerson SG, Palsson BO, Clarke MF, Silver SM, Adams PT, Koller MR, Van Zant G, Rummel S, Armstrong RD, Maluta J. Cancer Treat Res. 1995: 76 215-23
• Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Sumantran VN, Ealovega MW, Nuñez G, Clarke MF, Wicha MS. Cancer Res. 1995; 55 (12): 2507-10
• Retroviral-mediated gene transfer in human bone marrow cells growth in continuous perfusion culture vessels. Eipers PG, Krauss JC, Palsson BO, Emerson SG, Todd RF, Clarke MF. Blood. 1995; 86 (10): 3754-62
• Alteration of p53 conformation and induction of apoptosis in a murine erythroleukemia cell line by dimethylsulfoxide. Ryan JJ, Clarke MF. Leuk Res. 1994; 18 (8): 617-21
• The Bcl-2 family of proteins: regulators of cell death and survival. Nuñez G, Clarke MF. Trends Cell Biol. 1994; 4 (11): 399-403
• c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle. Ryan JJ, Prochownik E, Gottlieb CA, Apel IJ, Merino R, Nuñez G, Clarke MF. Proc Natl Acad Sci U S A. 1994; 91 (13): 5878-82
• Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells. Ryan JJ, Danish R, Gottlieb CA, Clarke MF. Mol Cell Biol. 1993; 13 (1): 711-9
• Can Dexter cultures support stem cell proliferation? Varma A, el-Awar FY, Palsson BO, Emerson SG, Clarke MF. Exp Hematol. 1992; 20 (1): 87-91
• Malignant transformation of NIH 3T3 fibroblasts by human c-sis is dependent upon the level of oncogene expression. MacArthur LH, Clarke MF, Westin EH. Mol Carcinog. 1992; 5 (4): 311-9
• The influence of extra-cellular matrix and stroma remodeling on the productivity of long-term human bone marrow cultures. Schwartz RM, Caldwell J, Clarke MF, Emerson SG, Palsson BO. Cytotechnology. 1992; 10 (3): 217-24
• c-myb effects on kinetic events during MEL cell differentiation. Danish R, el-Awar O, Weber BL, Langmore J, Turka LA, Ryan JJ, Clarke MF. Oncogene. 1992; 7 (5): 901-7
• Biotinylated granulocyte/macrophage colony-stimulating factor analogues: effect of linkage chemistry on activity and binding. Angelotti TP, Clarke MF, Longino MA, Emerson SG. Bioconjug Chem. 1991 Nov-Dec; 2 (6): 466-74
• Influence of medium exchange schedules on metabolic, growth, and GM-CSF secretion rates of genetically engineered NIH-3T3 cells. Caldwell J, Locey B, Clarke MF, Emerson SG, Palsson BO. Biotechnol Prog. 1991 Jan-Feb; 7 (1): 1-8
• In vitro myelopoiesis stimulated by rapid medium exchange and supplementation with hematopoietic growth factors. Schwartz RM, Emerson SG, Clarke MF, Palsson BO. Blood. 1991; 78 (12): 3155-61
• The construction of high efficiency human bone marrow tissue ex vivo. Emerson SG, Palsson BO, Clarke MF. J Cell Biochem. 1991; 45 (3): 268-72
• Alternative splicing of the human c-myb gene. Westin EH, Gorse KM, Clarke MF. Oncogene. 1990; 5 (8): 1117-24
• Differentiation of mouse erythroleukemia cells enhanced by alternatively spliced c-myb mRNA. Weber BL, Westin EH, Clarke MF. Science. 1990; 249 (4974): 1291-3
• The proliferation of AML-193 is regulated by multiple hematopoietic growth factors and cytokines. Adams S, Upadhyaya G, Clarke MF, Emerson SG. Leukemia. 1989; 3 (4): 314-5
• Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Clarke MF, Kukowska-Latallo JF, Westin E, Smith M, Prochownik EV. Mol Cell Biol. 1988; 8 (2): 884-92
• Activation of a novel KpnI transcript by downstream integration of a human T-lymphotropic virus type I provirus. Okamoto T, Reitz MS, Clarke MF, Jagodzinski LL, Wong-Staal F. J Biol Chem. 1986; 261 (10): 4615-9
• Sequence-specific interaction of histones with the simian virus 40 enhancer region in vitro. Clarke MF, FitzGerald PC, Brubaker JM, Simpson RT. J Biol Chem. 1985; 260 (23): 12394-7
• Transformation of NIH 3T3 cells by a human c-sis cDNA clone. Clarke MF, Westin E, Schmidt D, Josephs SF, Ratner L, Wong-Staal F, Gallo RC, Reitz MS. Nature. 1984 Mar 29-Apr 4; 308 (5958): 464-7
• DNA methylation and expression of HLA-DR alpha. Reitz MS, Mann DL, Eiden M, Trainor CD, Clarke MF. Mol Cell Biol. 1984; 4 (5): 890-7
• Differential methylation of class I histocompatibility antigen genes in T-cell lines derived from two different types of T-cell malignancies. Clarke MF, Mann DL, Murray C, Reitz MS. Leuk Res. 1984; 8 (6): 965-73
• Identification of the human T cell lymphoma virus in B cell lines established from patients with adult T cell leukemia. Mann DL, Clark J, Clarke M, Reitz M, Popovic M, Franchini G, Trainor CD, Strong DM, Blattner WA, Gallo RC. J Clin Invest. 1984; 74 (1): 56-62
• Methylation of human T-cell leukemia virus proviral DNA and viral RNA expression in short- and long-term cultures of infected cells. Clarke MF, Trainor CD, Mann DL, Gallo RC, Reitz MS. Virology. 1984; 135 (1): 97-104
• Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor. Josephs SF, Ratner L, Clarke MF, Westin EH, Reitz MS, Wong-Staal F. Science. 1984; 225 (4662): 636-9
• Homology of human T-cell leukaemia virus envelope gene with class I HLA gene. Clarke MF, Gelmann EP, Reitz MS. Nature. 1983 Sep 1-7; 305 (5929): 60-2
• Presence of HTLV in a subset of T cells from an infected patient: some immunochemical properties of the infected cells. Reitz MS, Mann D, Clarke MF, Kalyanaraman VS, Robert-Guroff M, Popovic M, Gallo RC. Haematol Blood Transfus. 1983: 28 459-61
• Relation of respiratory burst and arachidonate metabolism during phagocytosis by guinea pig alveolar macrophages. Ingraham LM, Weening RS, Clarke MF, Boxer LA, Baehner RL. J Lab Clin Med. 1982; 99 (6): 908-16