Phillip C. Yang, MD

Publications

• Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells. Wang IN, Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC. PLoS One. 2012; 7 (6): e38328
• Bone marrow cell therapy in clinical trials: a review of the literature. Kim PJ, Yang PC. Rev Recent Clin Trials. 2012; 7 (3): 204-13
• Human amniotic mesenchymal stem cell-derived induced pluripotent stem cells may generate a universal source of cardiac cells. Ge X, Wang IN, Toma I, Sebastiano V, Liu J, Butte MJ, Reijo Pera RA, Yang PC. Stem Cells Dev. 2012; 21 (15): 2798-808
• In vivo detection and treatment of ischemia-induced cardiac apoptosis using an MRI-detectable molecular probe and an alpha-adrenergic receptor agonist. Lam J, Toma I, Gong Y, Simpson PC, Robbins RC, Yang PC, Dash R. J Cardiovasc Magn Reson. 2012: 14 Suppl 1 P67
• Is reliable in vivo detection of stem cell viability possible in a large animal model of myocardial injury? Yang PC, Circulation. 2012; 126 (4): 388-90
• Manganese-enhanced MRI detects live human amnion-derived mesenchymal stem cells in vivo after transplantation and restoration of myocardial function in a pig ischemia-reperfusion injury model. Dash R, Toma I, Ikeno F, Lyons JK, Heidary S, Parent MC, Wang IE, Ge X, Chung J, Lam J, Kim PJ, Nakagawa K, Lyalina S, Do G, Robbins RC, McConnell MV, Yeung A, Harnish P, Yang PC. J Cardiovasc Magn Reson. 2012: 14 Suppl 1 P62
• Manganese-enhanced MRI in the evaluation of cell-based therapy for myocardial restoration. Kim PJ, Toma I, Wang IE, Yang PC. J Cardiovasc Magn Reson. 2012: 14 Suppl 1 P50
• Synthesis of an in vivo MRI-detectable apoptosis probe. Lam J, Simpson PC, Yang PC, Dash R. J Vis Exp. 2012; (65)
• Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma. Chung J, Dash R, Kee K, Barral JK, Kosuge H, Robbins RC, Nishimura D, Reijo-Pera RA, Yang PC. Magn Reson Med. 2012; 68 (2): 595-9
• A molecular MRI probe to detect treatment of cardiac apoptosis in vivo. Dash R, Chung J, Chan T, Yamada M, Barral J, Nishimura D, Yang PC, Simpson PC. Magn Reson Med. 2011; 66 (4): 1152-62
• Contrast echocardiography: finding its place in stem cell therapy. Kim PJ, Yang PC. Minerva Cardioangiol. 2011; 59 (5): 491-7
• Dual manganese-enhanced and delayed gadolinium-enhanced MRI detects myocardial border zone injury in a pig ischemia-reperfusion model. Dash R, Chung J, Ikeno F, Hahn-Windgassen A, Matsuura Y, Bennett MV, Lyons JK, Teramoto T, Robbins RC, McConnell MV, Yeung AC, Brinton TJ, Harnish PP, Yang PC. Circ Cardiovasc Imaging. 2011; 4 (5): 574-82
• In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium. Chung J, Kee K, Barral JK, Dash R, Kosuge H, Wang X, Weissman I, Robbins RC, Nishimura D, Quertermous T, Reijo-Pera RA, Yang PC. Magn Reson Med. 2011; 66 (5): 1374-81
• αB-crystallin improves murine cardiac function and attenuates apoptosis in human endothelial cells exposed to ischemia-reperfusion. Velotta JB, Kimura N, Chang SH, Chung J, Itoh S, Rothbard J, Yang PC, Steinman L, Robbins RC, Fischbein MP. Ann Thorac Surg. 2011; 91 (6): 1907-13
• Molecular Imaging of Stem Cell Transplantation in Myocardial Disease. Chung J, Yang PC. Curr Cardiovasc Imaging Rep. 2010; 3 (2): 106-112
• Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea. Nguyen PK, Katikireddy CK, McConnell MV, Kushida C, Yang PC. J Cardiovasc Magn Reson. 2010: 12 50
• Quantitative tissue characterization of infarct core and border zone in patients with ischemic cardiomyopathy by magnetic resonance is associated with future cardiovascular events. Heidary S, Patel H, Chung J, Yokota H, Gupta SN, Bennett MV, Katikireddy C, Nguyen P, Pauly JM, Terashima M, McConnell MV, Yang PC. J Am Coll Cardiol. 2010; 55 (24): 2762-8
• Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Mol Imaging Biol. 2009 May-Jun; 11 (3): 178-87
• Magnetic resonance imaging of human embryonic stem cells. Chung J, Yamada M, Yang PC. Curr Protoc Stem Cell Biol. 2009: Chapter 5 Unit 5A.3
• Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability. Yamada M, Gurney PT, Chung J, Kundu P, Drukker M, Smith AK, Weissman IL, Nishimura D, Robbins RC, Yang PC. Magn Reson Med. 2009; 62 (4): 1047-54
• Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC. Stem Cells. 2008; 26 (4): 864-73
• Human ESC vs. iPSC-pros and cons. Pappas JJ, Yang PC. J Cardiovasc Transl Res. 2008; 1 (2): 96-9
• In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast. Suzuki Y, Cunningham CH, Noguchi K, Chen IY, Weissman IL, Yeung AC, Robbins RC, Yang PC. Magn Reson Med. 2008; 60 (6): 1269-75
• Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. Hendry SL, van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC. J Thorac Cardiovasc Surg. 2008; 136 (4): 1028-1037.e1
• Multimodality evaluation of the viability of stem cells delivered into different zones of myocardial infarction. Hung TC, Suzuki Y, Urashima T, Caffarelli A, Hoyt G, Sheikh AY, Yeung AC, Weissman I, Robbins RC, Bulte JW, Bulte JM, Yang PC. Circ Cardiovasc Imaging. 2008; 1 (1): 6-13
• Quantitative characterization of myocardial infarction by cardiovascular magnetic resonance predicts future cardiovascular events in patients with ischemic cardiomyopathy. Yokota H, Heidary S, Katikireddy CK, Nguyen P, Pauly JM, McConnell MV, Yang PC. J Cardiovasc Magn Reson. 2008: 10 17
• Cardiovascular MRI for stem cell therapy. Suzuki Y, Yeung AC, Yang PC. Curr Cardiol Rep. 2007; 9 (1): 45-50
• In vitro comparison of the biological effects of three transfection methods for magnetically labeling mouse embryonic stem cells with ferumoxides. Suzuki Y, Zhang S, Kundu P, Yeung AC, Robbins RC, Yang PC. Magn Reson Med. 2007; 57 (6): 1173-9
• Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse. Yue P, Arai T, Terashima M, Sheikh AY, Cao F, Charo D, Hoyt G, Robbins RC, Ashley EA, Wu J, Yang PC, Tsao PS. Am J Physiol Heart Circ Physiol. 2007; 292 (5): H2106-18
• Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Kutschka I, Chen IY, Kofidis T, Arai T, von Degenfeld G, Sheikh AY, Hendry SL, Pearl J, Hoyt G, Sista R, Yang PC, Blau HM, Gambhir SS, Robbins RC. Circulation. 2006; 114 (1 Suppl): I167-73
• Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t. Arai T, Kofidis T, Bulte JW, de Bruin J, Venook RD, Berry GJ, Mcconnell MV, Quertermous T, Robbins RC, Yang PC. Magn Reson Med. 2006; 55 (1): 203-9
• FeCo/graphitic-shell nanocrystals as advanced magnetic-resonance-imaging and near-infrared agents. Seo WS, Lee JH, Sun X, Suzuki Y, Mann D, Liu Z, Terashima M, Yang PC, McConnell MV, Nishimura DG, Dai H. Nat Mater. 2006; 5 (12): 971-6
• Images in cardiovascular medicine. Cardiac magnetic resonance imaging for myocarditis: effective use in medical decision making. Fenster BE, Chan FP, Valentine HA, Yang E, McConnell MV, Berry GJ, Yang PC. Circulation. 2006; 113 (22): e842-3
• Indirect magnetic resonance lymphangiography to assess lymphatic function in experimental murine lymphedema. Pan D, Suzuki Y, Yang PC, Rockson SG. Lymphat Res Biol. 2006; 4 (4): 211-6
• Peri-infarct ischemia determined by cardiovascular magnetic resonance evaluation of myocardial viability and stress perfusion predicts future cardiovascular events in patients with severe ischemic cardiomyopathy. Tsukiji M, Nguyen P, Narayan G, Hellinger J, Chan F, Herfkens R, Pauly JM, McConnell MV, Yang PC. J Cardiovasc Magn Reson. 2006; 8 (6): 773-9
• Real-time color-flow CMR in adults with congenital heart disease. de la Pena E, Nguyen PK, Nayak KS, Yang PC, Rosenthal DN, Hu BS, Pauly JM, McConnell MV. J Cardiovasc Magn Reson. 2006; 8 (6): 809-15
• Early diagnosis of hemochromatosis-related cardiomyopathy with magnetic resonance imaging. Ptaszek LM, Price ET, Hu MY, Yang PC. J Cardiovasc Magn Reson. 2005; 7 (4): 689-92
• High-resolution real-time spiral MRI for guiding vascular interventions in a rabbit model at 1.5 T. Terashima M, Hyon M, de la Pena-Almaguer E, Yang PC, Hu BS, Nayak KS, Pauly JM, McConnell MV. J Magn Reson Imaging. 2005; 22 (5): 687-90
• Noninvasive assessment of coronary vasodilation using magnetic resonance angiography. Terashima M, Meyer CH, Keeffe BG, Putz EJ, de la Pena-Almaguer E, Yang PC, Hu BS, Nishimura DG, McConnell MV. J Am Coll Cardiol. 2005; 45 (1): 104-10
• Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles. Cunningham CH, Arai T, Yang PC, McConnell MV, Pauly JM, Conolly SM. Magn Reson Med. 2005; 53 (5): 999-1005
• Dynamic real-time architecture in magnetic resonance coronary angiography--a prospective clinical trial. Yang PC, Santos JM, Nguyen PK, Scott GC, Engvall J, McConnell MV, Wright GA, Nishimura DG, Pauly JM, Hu BS. J Cardiovasc Magn Reson. 2004; 6 (4): 885-94
• Spiral magnetic resonance coronary angiography--direct comparison of 1.5 Tesla vs. 3 Tesla. Yang PC, Nguyen P, Shimakawa A, Brittain J, Pauly J, Nishimura D, Hu B, McConnell M. J Cardiovasc Magn Reson. 2004; 6 (4): 877-84
• A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. Hope MD, de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN. J Am Soc Echocardiogr. 2003; 16 (8): 824-31
• Magnetic resonance coronary angiography. Yang PC, McConnell MV, Nishimura DG, Hu BS. Curr Cardiol Rep. 2003; 5 (1): 55-62
• Spiral magnetic resonance coronary angiography with rapid real-time localization. Yang PC, Meyer CH, Terashima M, Kaji S, McConnell MV, Macovski Al, Pauly JM, Nishimura DG, Hu BS. J Am Coll Cardiol. 2003; 41 (7): 1134-41
• Rapid evaluation of left ventricular volume and mass without breath-holding using real-time interactive cardiac magnetic resonance imaging system. Kaji S, Yang PC, Kerr AB, Tang WH, Meyer CH, Macovski A, Pauly JM, Nishimura DG, Hu BS. J Am Coll Cardiol. 2001; 38 (2): 527-33
• Real-time interactive coronary MRA. Nayak KS, Pauly JM, Yang PC, Hu BS, Meyer CH, Nishimura DG. Magn Reson Med. 2001; 46 (3): 430-5
• New real-time interactive cardiac magnetic resonance imaging system complements echocardiography. Yang PC, Kerr AB, Liu AC, Liang DH, Hardy C, Meyer CH, Macovski A, Pauly JM, Hu BS. J Am Coll Cardiol. 1998; 32 (7): 2049-56