Lawrence Chu, MD, MS

Publications

• Analgesic tolerance without demonstrable opioid-induced hyperalgesia: a double-blinded, randomized, placebo-controlled trial of sustained-release morphine for treatment of chronic nonradicular low-back pain. Chu LF, D'Arcy N, Brady C, Zamora AK, Young CA, Kim JE, Clemenson AM, Angst MS, Clark JD. Pain. 2012; 153 (8): 1583-92
• Information technology and its role in anaesthesia training and continuing medical education. Chu LF, Erlendson MJ, Sun JS, Clemenson AM, Martin P, Eng RL. Best Pract Res Clin Anaesthesiol. 2012; 26 (1): 33-53
• Mobile computing in medical education: opportunities and challenges. Chu LF, Erlendson MJ, Sun JS, Alva HL, Clemenson AM. Curr Opin Anaesthesiol. 2012; 25 (6): 699-718
• Modulation of remifentanil-induced postinfusion hyperalgesia by the β-blocker propranolol in humans. Chu LF, Cun T, Ngai LK, Kim JE, Zamora AK, Young CA, Angst MS, Clark DJ. Pain. 2012; 153 (5): 974-81
• A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry. Clavijo CF, Hoffman KL, Thomas JJ, Carvalho B, Chu LF, Drover DR, Hammer GB, Christians U, Galinkin JL. Anal Bioanal Chem. 2011; 400 (3): 715-28
• Analysis of 4999 online physician ratings indicates that most patients give physicians a favorable rating. Kadry B, Chu LF, Kadry B, Gammas D, Macario A. J Med Internet Res. 2011; 13 (4): e95
• Prescription opioid analgesics rapidly change the human brain. Younger JW, Chu LF, D'Arcy NT, Trott KE, Jastrzab LE, Mackey SC. Pain. 2011; 152 (8): 1803-10
• Self-reported information needs of anesthesia residency applicants and analysis of applicant-related web sites resources at 131 United States training programs. Chu LF, Young CA, Zamora AK, Lowe D, Hoang DB, Pearl RG, Macario A. Anesth Analg. 2011; 112 (2): 430-9
• The endogenous opioid system is not involved in modulation of opioid-induced hyperalgesia. Chu LF, Dairmont J, Zamora AK, Young CA, Angst MS. J Pain. 2011; 12 (1): 108-15
• Anesthesia 2.0: internet-based information resources and Web 2.0 applications in anesthesia education. Chu LF, Young C, Zamora A, Kurup V, Macario A. Curr Opin Anaesthesiol. 2010; 23 (2): 218-27
• Finite element modeling of subcutaneous implantable defibrillator electrodes in an adult torso. Jolley M, Stinstra J, Tate J, Pieper S, Macleod R, Chu L, Wang P, Triedman JK. Heart Rhythm. 2010; 7 (5): 692-8
• Learning management systems and lecture capture in the medical academic environment. Chu LF, Young CA, Ngai LK, Cun T, Pearl RG, Macario A. Int Anesthesiol Clin. 2010; 48 (3): 27-51
• The role of social networking applications in the medical academic environment. Chu LF, Zamora AK, Young CA, Kurup V, Macario A. Int Anesthesiol Clin. 2010; 48 (3): 61-82
• Anesthesia-controlled time and turnover time for ambulatory upper extremity surgery performed with regional versus general anesthesia. Mariano ER, Chu LF, Peinado CR, Mazzei WJ. J Clin Anesth. 2009; 21 (4): 253-7
• Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery. Mariano ER, Watson D, Loland VJ, Chu LF, Cheng GS, Mehta SH, Maldonado RC, Ilfeld BM. Can J Anaesth. 2009; 56 (8): 584-9
• From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. Chu LF, Liang DY, Li X, Sahbaie P, D'arcy N, Liao G, Peltz G, David Clark J. Pharmacogenet Genomics. 2009; 19 (3): 193-205
• Molecular Basis and Clinical Implications of Opioid Tolerance and Opioid-induced Hyperalgesia Chu LF, Angst MS, Clark DJ. Acute Pain Management, Cambridge University Press, New York, New York. 2009
• No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans. Angst MS, Chu LF, Tingle MS, Shafer SL, Clark JD, Drover DR. Pain. 2009; 142 (1-2): 17-26
• Ondansetron: an effective treatment for the withdrawal symptoms of opioids? Chu LF, Clark DJ. Therapy. 2009; 6 (5): 637-640
• Overview on Clinical Features of Opioid-Induced Hyperalgesia. Angst M, Chu L, Clark J.. Opioid-Induced Hyperalgesia.. 2009: 21-37
• Opioid-induced hyperalgesia in humans: molecular mechanisms and clinical considerations. Chu LF, Angst MS, Clark D. Clin J Pain. 2008 Jul-Aug; 24 (6): 479-96
• Comparative evaluation of noninvasive compression adjuncts for hemostasis in percutaneous arterial, venous, and arteriovenous dialysis access procedures. Wang DS, Chu LF, Olson SE, Miller FJ, Valji K, Wong WH, Rose SC, Austin M, Kuo MD. J Vasc Interv Radiol. 2008; 19 (1): 72-9
• Comparison of supplementation rates for perivascular axillary and coracoid infraclavicular blocks in ambulatory upper extremity surgery. Mariano ER, Cheng GS, Loland VJ, Chu LF.. Ambulatory Surgery. 2008; 14 (2): 95-109
• Reduced cold pain tolerance in chronic pain patients following opioid detoxification. Younger J, Barelka P, Carroll I, Kaplan K, Chu L, Prasad R, Gaeta R, Mackey S. Pain Med. 2008; 9 (8): 1158-63
• Ketamine does not increase pulmonary vascular resistance in children with pulmonary hypertension undergoing sevoflurane anesthesia and spontaneous ventilation. Williams GD, Philip BM, Chu LF, Boltz MG, Kamra K, Terwey H, Hammer GB, Perry SB, Feinstein JA, Ramamoorthy C. Anesth Analg. 2007; 105 (6): 1578-84, table of contents
• Single-dose, extended-release epidural morphine (DepoDur) compared to conventional epidural morphine for post-cesarean pain. Carvalho B, Roland LM, Chu LF, Campitelli VA, Riley ET. Anesth Analg. 2007; 105 (1): 176-83
• Communication in critical care environments: mobile telephones improve patient care. Soto RG, Chu LF, Goldman JM, Rampil IJ, Ruskin KJ. Anesth Analg. 2006; 102 (2): 535-41
• Modified and conventional ultrafiltration during pediatric cardiac surgery: clinical outcomes compared. Williams GD, Ramamoorthy C, Chu L, Hammer GB, Kamra K, Boltz MG, Pentcheva K, McCarthy JP, Reddy VM. J Thorac Cardiovasc Surg. 2006; 132 (6): 1291-8
• Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study. Chu LF, Clark DJ, Angst MS. J Pain. 2006; 7 (1): 43-8
• Scheduling elective pediatric procedures that require anesthesia: the perspective of parents. Mariano ER, Chu LF, Ramamoorthy C, Macario A. Anesth Analg. 2006; 103 (6): 1426-31
• Valdecoxib for postoperative pain management after cesarean delivery: a randomized, double-blind, placebo-controlled study. Carvalho B, Chu L, Fuller A, Cohen SE, Riley ET. Anesth Analg. 2006; 103 (3): 664-70
• A comparison of three methods for estimating appropriate tracheal tube depth in children. Mariano ER, Ramamoorthy C, Chu LF, Chen M, Hammer GB. Paediatr Anaesth. 2005; 15 (10): 846-51
• Clinical Anesthesiology Board Review Chu, LF, McGraw-Hill Medical Publishing. 2005
• Successful thoracoscopic repair of esophageal atresia with tracheoesophageal fistula in a newborn with single ventricle physiology. Mariano ER, Chu LF, Albanese CT, Ramamoorthy C. Anesth Analg. 2005; 101 (4): 1000-2, table of contents
• Different molecular forms of uncomplexed prostate specific antigen (PSA) show similar immunoreactivities. Chu LF, Chen Z, Stamey TA. J Urol. 1999; 161 (6): 2009-12
• Evolution of web site design: implications for medical education on the Internet. Chu LF, Chan BK. Comput Biol Med. 1998; 28 (5): 459-72
• Adherence of mononuclear cells to endothelium in vitro is increased in patients with NIDDM. Carantoni M, Abbasi F, Chu L, Chen YD, Reaven GM, Tsao PS, Varasteh B, Cooke JP. Diabetes Care. 1997; 20 (9): 1462-5
• One-step HPLC purification procedure for porcine brain 90-kDa heat shock protein. Chu LF, Lee WC, Yang PC, Chu R, Huang TY, Mao SJ. Protein Expr Purif. 1997; 10 (2): 180-4
• Microtubule movement by a biotinated kinesin bound to streptavidin-coated surface. Berliner E, Mahtani HK, Karki S, Chu LF, Cronan JE, Gelles J. J Biol Chem. 1994; 269 (11): 8610-5