Andrew J. Patterson, M.D., Ph.D.

Publications

• FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats Ghebremariam YT, Yamada K, Lee JC, Johnson CLC, Atzler D, Anderssohn M, Agrawal R, Higgins JP, Patterson AJ, Boger RH, Cooke JP. PLos ONE. 2013; 83 (4): e60653
• Cardiovascular management of septic shock in 2012. Guillamet MC, Rhee C, Patterson AJ. Curr Infect Dis Rep. 2012; 14 (5): 493-502
• Mice Lacking the Beta 2 Adrenergic Receptor have a Unique Genetic Profile Before and After Focal Brain Ischemia White RE, Palm CJ, Xu L, Ling EB, Ginsburg M, Daigle Jr BJ, Han R, Patterson AJ, Altman RB, Giffard RG. ASN Neuro. 2012; Epub (Aug 6): XXX
• Potential for overuse of corticosteroids and vasopressin in septic shock. Hsu JL, Liu V, Patterson AJ, Martin GS, Nicolls MR, Russell JA. Crit Care. 2012; 16 (5): 447
• Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension. Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung YK, Gera L, Patterson AJ, Agrawal R, Rabinovitch M, Ambler K, Long CS, Voelkel NF, Nicolls MR. Circ Res. 2011; 109 (8): 867-79
• Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis. Wong J, Chang C, Agrawal R, Walton GB, Chen C, Murthy A, Patterson AJ. Crit Care Med. 2010; 38 (1): 25-31
• Genetic polymorphisms in sepsis. Namath A, Patterson AJ. Crit Care Clin. 2009; 25 (4): 835-56, x
• Postischemic brain injury is attenuated in mice lacking the beta2-adrenergic receptor. Han RQ, Ouyang YB, Xu L, Agrawal R, Patterson AJ, Giffard RG. Anesth Analg. 2009; 108 (1): 280-7
• Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. J Clin Invest. 2008; 118 (10): 3343-54
• Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4. Richter W, Day P, Agrawal R, Bruss MD, Granier S, Wang YL, Rasmussen SG, Horner K, Wang P, Lei T, Patterson AJ, Kobilka B, Conti M. EMBO J. 2008; 27 (2): 384-93
• Impact of Phosphodiesterase 4D on Cardiac beta2 Adrenergic Receptor Signaling Patterson AJ, Pearl N, Chang C. Seminars in Anesthesia, Perioperative Medicine, and Pain. 2007; 26 (1): 22-27
• Ushering in the Era of Nuclear Terrorism Patterson AJ, Critical Care Medicine. 2007; 35 (3): 953-954
• beta1 and beta2 Adrenergic Receptor Polymorphisms: Their Impact on Cardiovascular Physiology, Disease States, and Response to Therapeutic Agents Namath A, Chen C, Agrawal R, Patterson AJ. Seminars in Anesthesia, Perioperative Medicine, and Pain. 2007; 26 (1): 2-9
• Fiberoptic light source-induced surgical fires -- the contribution of forced-air warming blankets. Williams DM, Littwin S, Patterson AJ, Brock-Utne JG. Acta Anaesthesiol Scand. 2006; 50 (4): 505-8
• Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Jacobi J, Sydow K, von Degenfeld G, Zhang Y, Dayoub H, Wang B, Patterson AJ, Kimoto M, Blau HM, Cooke JP. Circulation. 2005; 111 (11): 1431-8
• The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A, Deng A, Eichhorn J, Mahajan R, Agrawal R, Greve J, Robbins R, Patterson AJ, Bernstein D, Quertermous T. Cardiovasc Res. 2005; 65 (1): 73-82
• Protecting the myocardium: a role for the beta2 adrenergic receptor in the heart. Patterson AJ, Zhu W, Chow A, Agrawal R, Kosek J, Xiao RP, Kobilka B. Crit Care Med. 2004; 32 (4): 1041-8
• Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Dayoub H, Achan V, Adimoolam S, Jacobi J, Stuehlinger MC, Wang BY, Tsao PS, Kimoto M, Vallance P, Patterson AJ, Cooke JP. Circulation. 2003; 108 (24): 3042-7
• Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation. Myles T, Nishimura T, Yun TH, Nagashima M, Morser J, Patterson AJ, Pearl RG, Leung LL. J Biol Chem. 2003; 278 (51): 51059-67
• Abnormal Cardiac Function Associated with Sympathetic Nervous System Hyperactivity in Mice Patrcia C. Brum, Jon Kosek, Andrew Patterson, Daniel Bernstein, Brian Kobilka. Am J Physiol Heart Circ Physiol. 2002: 283 H1838-H1845
• Vasoregulation at the molecular level: a role for the beta1 subunit of the calcium-activated potassium (BK) channel. Patterson AJ, Henrie-Olson J, Brenner R. Trends Cardiovasc Med. 2002; 12 (2): 78-82
• Vasoregulation by the beta1 subunit of the calcium-activated potassium channel. Brenner R, Peréz GJ, Bonev AD, Eckman DM, Kosek JC, Wiler SW, Patterson AJ, Nelson MT, Aldrich RW. Nature. 2000; 407 (6806): 870-6
• Nitrous oxide produces antinociceptive response via alpha2B and/or alpha2C adrenoceptor subtypes in mice. Guo TZ, Davies MF, Kingery WS, Patterson AJ, Limbird LE, Maze M. Anesthesiology. 1999; 90 (2): 470-6
• Airway obstruction caused by an oleothorax. Patterson AJ, Leong MS, Brodsky JB, Mark JB. J Cardiothorac Vasc Anesth. 1998; 12 (2): 189-91