Publications
-
Cost-effectiveness of modern radiotherapy techniques in locally advanced pancreatic cancer.
Murphy JD,
Chang DT, Abelson J, Daly ME, Yeung HN, Nelson LM, Koong AC.
Cancer.
2012;
118
(4):
1119-29
-
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.
Papandreou I,
Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC.
Blood.
2011;
117
(4):
1311-4
-
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth.
Spiotto MT,
Banh A, Papandreou I, Cao H, Galvez MG, Gurtner GC, Denko NC, Le QT, Koong AC.
Cancer Res.
2010;
70
(1):
78-88
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Erler JT,
Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ.
Cancer Cell.
2009;
15
(1):
35-44
-
Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas.
Chang DT,
Schellenberg D, Shen J, Kim J, Goodman KA, Fisher GA, Ford JM, Desser T, Quon A, Koong AC.
Cancer.
2009;
115
(3):
665-72
-
The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth.
Bennewith KL,
Huang X, Ham CM, Graves EE, Erler JT, Kambham N, Feazell J, Yang GP, Koong A, Giaccia AJ.
Cancer Res.
2009;
69
(3):
775-84
-
X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.
Romero-Ramirez L,
Cao H, Regalado MP, Kambham N, Siemann D, Kim JJ, Le QT, Koong AC.
Transl Oncol.
2009;
2
(1):
31-8
-
Multiplexed protein detection by proximity ligation for cancer biomarker validation.
Fredriksson S,
Dixon W, Ji H, Koong AC, Mindrinos M, Davis RW.
Nat Methods.
2007;
4
(4):
327-9
-
Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis.
Dornhöfer N,
Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Nacalumi R, Höckel M, Le Q, Longaker M, Yang G, Koong A, Giaccia A.
Cancer Res.
2006;
66
(11):
5816-27
-
Galectin-1: a link between tumor hypoxia and tumor immune privilege.
Le QT,
Shi G, Cao H, Nelson DW, Wang Y, Chen EY, Zhao S, Kong C, Richardson D, O'Byrne KJ, Giaccia AJ, Koong AC.
J Clin Oncol.
2005;
23
(35):
8932-41
-
The unfolded protein response: a novel component of the hypoxic stress response in tumors.
Feldman DE,
Chauhan V, Koong AC.
Mol Cancer Res.
2005;
3
(11):
597-605
-
Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling.
Chen Y,
Shi G, Xia W, Kong C, Zhao S, Gaw AF, Chen EY, Yang GP, Giaccia AJ, Le QT, Koong AC.
Cancer Res.
2004;
64
(20):
7302-10
-
Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer.
Koong AC,
Le QT, Ho A, Fong B, Fisher G, Cho C, Ford J, Poen J, Gibbs IC, Mehta VK, Kee S, Trueblood W, Yang G, Bastidas JA.
Int J Radiat Oncol Biol Phys.
2004;
58
(4):
1017-21
-
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.
Romero-Ramirez L,
Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC.
Cancer Res.
2004;
64
(17):
5943-7
-
Candidate genes for the hypoxic tumor phenotype.
Koong AC,
Denko NC, Hudson KM, Schindler C, Swiersz L, Koch C, Evans S, Ibrahim H, Le QT, Terris DJ, Giaccia AJ.
Cancer Res.
2000;
60
(4):
883-7
-
Loss of PTEN facilitates HIF-1-mediated gene expression.
Zundel W,
Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ.
Genes Dev.
2000;
14
(4):
391-6
-
Pancreatic tumors show high levels of hypoxia.
Koong AC,
Mehta VK, Le QT, Fisher GA, Terris DJ, Brown JM, Bastidas AJ, Vierra M.
Int J Radiat Oncol Biol Phys.
2000;
48
(4):
919-22
-
A novel epidermal growth factor receptor variant lacking multiple domains directly activates transcription and is overexpressed in tumors.
Piccione EC,
Lieu TJ, Gentile CF, Williams TR, Connolly AJ, Godwin AK, Koong AC, Wong AJ.
Oncogene.
2012;
31
(24):
2953-67
-
Antiangiogenic and radiation therapy: early effects on in vivo computed tomography perfusion parameters in human colon cancer xenografts in mice.
Ren Y,
Fleischmann D, Foygel K, Molvin L, Lutz AM, Koong AC, Jeffrey RB, Tian L, Willmann JK.
Invest Radiol.
2012;
47
(1):
25-32
-
BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features.
Pai RK,
Jayachandran P, Koong AC, Chang DT, Kwok S, Ma L, Arber DA, Balise RR, Tubbs RR, Shadrach B, Pai RK.
Am J Surg Pathol.
2012;
36
(5):
744-52
-
Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features.
Chang DT,
Pai RK, Rybicki LA, Dimaio MA, Limaye M, Jayachandran P, Koong AC, Kunz PA, Fisher GA, Ford JM, Welton M, Shelton A, Ma L, Arber DA, Pai RK.
Mod Pathol.
2012;
25
(8):
1128-39
-
Evaluation of the geometric accuracy of surrogate-based gated VMAT using intrafraction kilovoltage x-ray images.
Li R,
Mok E, Han B, Koong A, Xing L.
Med Phys.
2012;
39
(5):
2686-93
-
Intensity-modulated radiotherapy for pancreatic adenocarcinoma.
Abelson JA,
Murphy JD, Minn AY, Chung M, Fisher GA, Ford JM, Kunz P, Norton JA, Visser BC, Poultsides GA, Koong AC, Chang DT.
Int J Radiat Oncol Biol Phys.
2012;
82
(4):
e595-601
-
Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images.
Li R,
Mok E, Chang DT, Daly M, Loo BW, Diehn M, Le QT, Koong A, Xing L.
Int J Radiat Oncol Biol Phys.
2012;
83
(5):
e709-15
-
Modern radiation therapy techniques for pancreatic cancer.
Trakul N,
Koong AC, Maxim PG, Chang DT.
Gastroenterol Clin North Am.
2012;
41
(1):
223-35
-
Normal tissue complication probability modeling of acute hematologic toxicity in patients treated with intensity-modulated radiation therapy for squamous cell carcinoma of the anal canal.
Bazan JG,
Luxton G, Mok EC, Koong AC, Chang DT.
Int J Radiat Oncol Biol Phys.
2012;
84
(3):
700-6
-
Orthovoltage intraoperative radiotherapy for locally advanced and recurrent colorectal cancer.
Daly ME,
Kapp DS, Maxim PG, Welton ML, Tran PT, Koong AC, Chang DT.
Dis Colon Rectum.
2012;
55
(6):
695-702
-
Positron emission tomography for predicting pathologic response after neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
Chennupati SK,
Quon A, Kamaya A, Pai RK, La T, Krakow TE, Graves E, Koong AC, Chang DT.
Am J Clin Oncol.
2012;
35
(4):
334-9
-
Postchemoradiotherapy positron emission tomography predicts pathologic response and survival in patients with esophageal cancer.
Jayachandran P,
Pai RK, Quon A, Graves E, Krakow TE, La T, Loo BW, Koong AC, Chang DT.
Int J Radiat Oncol Biol Phys.
2012;
84
(2):
471-7
-
Quantitation of human papillomavirus DNA in plasma of oropharyngeal carcinoma patients.
Cao H,
Banh A, Kwok S, Shi X, Wu S, Krakow T, Khong B, Bavan B, Bala R, Pinsky BA, Colevas D, Pourmand N, Koong AC, Kong CS, Le QT.
Int J Radiat Oncol Biol Phys.
2012;
82
(3):
e351-8
-
WE-C-BRB-05: Monte Carlo Simulations and Experimental Validation of Rapid Dose Delivery with Very High-Energy Electron Beams.
Bazalova M,
Maxim P, Tantawi S, Colby E, Koong A, Loo B.
Med Phys.
2012;
39
(6):
3944
-
A novel aldehyde dehydrogenase-3 activator leads to adult salivary stem cell enrichment in vivo.
Banh A,
Xiao N, Cao H, Chen CH, Kuo P, Krakow T, Bavan B, Khong B, Yao M, Ha C, Kaplan MJ, Sirjani D, Jensen K, Kong CS, Mochly-Rosen D, Koong AC, Le QT.
Clin Cancer Res.
2011;
17
(23):
7265-72
-
Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal.
Bazan JG,
Hara W, Hsu A, Kunz PA, Ford J, Fisher GA, Welton ML, Shelton A, Kapp DS, Koong AC, Goodman KA, Chang DT.
Cancer.
2011;
117
(15):
3342-51
-
Stereotactic body radiation therapy for gastrointestinal malignancies.
Minn AY,
Koong AC, Chang DT.
Front Radiat Ther Oncol.
2011:
43
412-27
-
Stereotactic body radiotherapy for colorectal liver metastases: a pooled analysis.
Chang DT,
Swaminath A, Kozak M, Weintraub J, Koong AC, Kim J, Dinniwell R, Brierley J, Kavanagh BD, Dawson LA, Schefter TE.
Cancer.
2011;
117
(17):
4060-9
-
Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis.
Banh A,
Zhang J, Cao H, Bouley DM, Kwok S, Kong C, Giaccia AJ, Koong AC, Le QT.
Cancer Res.
2011;
71
(13):
4423-31
-
Unfolded protein response regulation in keloid cells.
Butler PD,
Wang Z, Ly DP, Longaker MT, Koong AC, Yang GP.
J Surg Res.
2011;
167
(1):
151-7
-
A dosimetric model of duodenal toxicity after stereotactic body radiotherapy for pancreatic cancer.
Murphy JD,
Christman-Skieller C, Kim J, Dieterich S, Chang DT, Koong AC.
Int J Radiat Oncol Biol Phys.
2010;
78
(5):
1420-6
-
Activation of the unfolded protein response in wound healing.
Wang Z,
Butler P, Ly D, Spiotto M, Koong A, Yang G.
J Surg Res.
2010;
158
(2):
209
-
Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma.
Niu G,
Sun X, Cao Q, Courter D, Koong A, Le QT, Gambhir SS, Chen X.
Clin Cancer Res.
2010;
16
(7):
2095-105
-
Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer.
Ho AS,
Huang X, Cao H, Christman-Skieller C, Bennewith K, Le QT, Koong AC.
Transl Oncol.
2010;
3
(2):
109-13
-
Comparison of intensity-modulated radiotherapy and 3-dimensional conformal radiotherapy as adjuvant therapy for gastric cancer.
Minn AY,
Hsu A, La T, Kunz P, Fisher GA, Ford JM, Norton JA, Visser B, Goodman KA, Koong AC, Chang DT.
Cancer.
2010;
116
(16):
3943-52
-
EUS-guided gold fiducial insertion for image-guided radiation therapy of pancreatic cancer: 50 successful cases without fluoroscopy.
Park WG,
Yan BM, Schellenberg D, Kim J, Chang DT, Koong A, Patalano C, Van Dam J.
Gastrointest Endosc.
2010;
71
(3):
513-8
-
Expression of p16(INK4A) but not hypoxia markers or poly adenosine diphosphate-ribose polymerase is associated with improved survival in patients with pancreatic adenocarcinoma.
Chang DT,
Chapman CH, Norton JA, Visser B, Fisher GA, Kunz P, Ford JM, Koong AC, Pai RK.
Cancer.
2010;
116
(22):
5179-87
-
Interfractional uncertainty in the treatment of pancreatic cancer with radiation.
Jayachandran P,
Minn AY, Van Dam J, Norton JA, Koong AC, Chang DT.
Int J Radiat Oncol Biol Phys.
2010;
76
(2):
603-7
-
Multimodality treatment with intensity modulated radiation therapy for esophageal cancer.
La TH,
Minn AY, Su Z, Fisher GA, Ford JM, Kunz P, Goodman KA, Koong AC, Chang DT.
Dis Esophagus.
2010;
23
(4):
300-8
-
Orthovoltage intraoperative radiation therapy for pancreatic adenocarcinoma.
Bachireddy P,
Tseng D, Horoschak M, Chang DT, Koong AC, Kapp DS, Tran PT.
Radiat Oncol.
2010:
5
105
-
Pathological response after chemoradiation for T3 rectal cancer.
Chennupati SK,
Kamaya A, Fisher GA, Ford JM, Kunz P, Itakura H, Welton ML, Shelton A, Van Dam J, Koong AC, Chang DT.
Colorectal Dis.
2010;
12
(7 Online):
e24-30
-
The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.
Courter D,
Cao H, Kwok S, Kong C, Banh A, Kuo P, Bouley DM, Vice C, Brustugun OT, Denko NC, Koong AC, Giaccia A, Le QT.
PLoS One.
2010;
5
(3):
e9633
-
A primer on image-guided radiation therapy for the interventional radiologist.
Kothary N,
Dieterich S, Louie JD, Koong AC, Hofmann LV, Sze DY.
J Vasc Interv Radiol.
2009;
20
(7):
859-62
-
Detection of solitary humeral metastasis from pancreatic adenocarcinoma with F-18 FDG PET/CT.
Kim J,
Quon A, Humke E, Ford JM, Koong AC.
Clin Nucl Med.
2009;
34
(5):
312-3
-
Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis.
Chang ST,
Zahn JM, Horecka J, Kunz PL, Ford JM, Fisher GA, Le QT, Chang DT, Ji H, Koong AC.
J Transl Med.
2009:
7
105
-
Impaired interferon signaling is a common immune defect in human cancer.
Critchley-Thorne RJ,
Simons DL, Yan N, Miyahira AK, Dirbas FM, Johnson DL, Swetter SM, Carlson RW, Fisher GA, Koong A, Holmes S, Lee PP.
Proc Natl Acad Sci U S A.
2009;
106
(22):
9010-5
-
Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.
Chen Y,
Cairns R, Papandreou I, Koong A, Denko NC.
PLoS One.
2009;
4
(9):
e7033
-
Pancreatic tumor motion on a single planning 4D-CT does not correlate with intrafraction tumor motion during treatment.
Minn AY,
Schellenberg D, Maxim P, Suh Y, McKenna S, Cox B, Dieterich S, Xing L, Graves E, Goodman KA, Chang D, Koong AC.
Am J Clin Oncol.
2009;
32
(4):
364-8
-
Re: "The safety and efficacy of robotic image-guided radiosurgery system treatment for intra- and extracranial lesions: a systematic review of the literature" [Radiotherapy and Oncology 89 (2009) 245-253].
Gibbs IC,
Levendag PC, Fariselli L, Bondiau PY, Lartigau E, Loo BW, Gagnon GJ, Koong A.
Radiother Oncol.
2009;
93
(3):
656-7
-
Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy.
Kothary N,
Heit JJ, Louie JD, Kuo WT, Loo BW, Koong A, Chang DT, Hovsepian D, Sze DY, Hofmann LV.
J Vasc Interv Radiol.
2009;
20
(2):
235-9
-
The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas.
Kong CS,
Narasimhan B, Cao H, Kwok S, Erickson JP, Koong A, Pourmand N, Le QT.
Int J Radiat Oncol Biol Phys.
2009;
74
(2):
553-61
-
Treatment of esophageal cancer based on histology: a surveillance epidemiology and end results analysis.
Chang DT,
Chapman C, Shen J, Su Z, Koong AC.
Am J Clin Oncol.
2009;
32
(4):
405-10
-
Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice.
Choi CY,
Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS, Giaccia AJ.
Mol Imaging.
2008 May-Jun;
7
(3):
139-46
-
Automated contour mapping with a regional deformable model.
Chao M,
Li T, Schreibmann E, Koong A, Xing L.
Int J Radiat Oncol Biol Phys.
2008;
70
(2):
599-608
-
Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer.
Schellenberg D,
Goodman KA, Lee F, Chang S, Kuo T, Ford JM, Fisher GA, Quon A, Desser TS, Norton J, Greco R, Yang GP, Koong AC.
Int J Radiat Oncol Biol Phys.
2008;
72
(3):
678-86
-
High-dose single-fraction radiotherapy: exploiting a new biology?
Brown JM,
Koong AC.
Int J Radiat Oncol Biol Phys.
2008;
71
(2):
324-5
-
In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma.
Le QT,
Koong A, Lieskovsky YY, Narasimhan B, Graves E, Pinto H, Brown JM, Spielman D.
Int J Radiat Oncol Biol Phys.
2008;
71
(4):
1151-7
-
Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer.
Quon A,
Chang ST, Chin F, Kamaya A, Dick DW, Loo BW, Gambhir SS, Koong AC.
Eur J Nucl Med Mol Imaging.
2008;
35
(3):
527-31
-
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Fredriksson S,
Horecka J, Brustugun OT, Schlingemann J, Koong AC, Tibshirani R, Davis RW.
Clin Chem.
2008;
54
(3):
582-9
-
Tissue effects after stereotactic body radiotherapy using cyberknife for patients with abdominal malignancies.
Cupp JS,
Koong AC, Fisher GA, Norton JA, Goodman KA.
Clin Oncol (R Coll Radiol).
2008;
20
(1):
69-75
-
Enhanced 4D cone-beam CT with inter-phase motion model.
Li T,
Koong A, Xing L.
Med Phys.
2007;
34
(9):
3688-95
-
Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma.
Daly ME,
Lieskovsky Y, Pawlicki T, Yau J, Pinto H, Kaplan M, Fee WE, Koong A, Goffinet DR, Xing L, Le QT.
Head Neck.
2007;
29
(3):
211-20
-
Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas.
Le QT,
Kong C, Lavori PW, O'byrne K, Erler JT, Huang X, Chen Y, Cao H, Tibshirani R, Denko N, Giaccia AJ, Koong AC.
Int J Radiat Oncol Biol Phys.
2007;
69
(1):
167-75
-
Impact of integrated PET/CT on variability of target volume delineation in rectal cancer.
Patel DA,
Chang ST, Goodman KA, Quon A, Thorndyke B, Gambhir SS, McMillan A, Loo BW, Koong AC.
Technol Cancer Res Treat.
2007;
6
(1):
31-6
-
Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody.
Cai W,
Chen K, He L, Cao Q, Koong A, Chen X.
Eur J Nucl Med Mol Imaging.
2007;
34
(6):
850-8
-
Stereotactic body radiotherapy for unresectable pancreatic cancer.
Chang ST,
Goodman KA, Yang GP, Koong AC.
Front Radiat Ther Oncol.
2007:
40
386-94
-
An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers.
Le QT,
Chen E, Salim A, Cao H, Kong CS, Whyte R, Donington J, Cannon W, Wakelee H, Tibshirani R, Mitchell JD, Richardson D, O'Byrne KJ, Koong AC, Giaccia AJ.
Clin Cancer Res.
2006;
12
(5):
1507-14
-
Four-dimensional cone-beam computed tomography using an on-board imager.
Li T,
Xing L, Munro P, McGuinness C, Chao M, Yang Y, Loo B, Koong A.
Med Phys.
2006;
33
(10):
3825-33
-
Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas.
Le QT,
Taira A, Budenz S, Jo Dorie M, Goffinet DR, Fee WE, Goode R, Bloch D, Koong A, Martin Brown J, Pinto HA.
Cancer.
2006;
106
(9):
1940-9
-
Overview of image-guided radiation therapy.
Xing L,
Thorndyke B, Schreibmann E, Yang Y, Li TF, Kim GY, Luxton G, Koong A.
Med Dosim.
2006;
31
(2):
91-112
-
Plasma osteopontin is an independent prognostic marker for head and neck cancers.
Petrik D,
Lavori PW, Cao H, Zhu Y, Wong P, Christofferson E, Kaplan MJ, Pinto HA, Sutphin P, Koong AC, Giaccia AJ, Le QT.
J Clin Oncol.
2006;
24
(33):
5291-7
-
Reducing respiratory motion artifacts in positron emission tomography through retrospective stacking.
Thorndyke B,
Schreibmann E, Koong A, Xing L.
Med Phys.
2006;
33
(7):
2632-41
-
Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors.
Le QT,
Loo BW, Ho A, Cotrutz C, Koong AC, Wakelee H, Kee ST, Constantinescu D, Whyte RI, Donington J.
J Thorac Oncol.
2006;
1
(8):
802-9
-
Targeting XBP-1 as a novel anti-cancer strategy.
Koong AC,
Chauhan V, Romero-Ramirez L.
Cancer Biol Ther.
2006;
5
(7):
756-9
-
A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia.
Nelson DW,
Cao H, Zhu Y, Sunar-Reeder B, Choi CY, Faix JD, Brown JM, Koong AC, Giaccia AJ, Le QT.
Cancer Res.
2005;
65
(14):
6151-8
-
Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer.
Zhu Y,
Denhardt DT, Cao H, Sutphin PD, Koong AC, Giaccia AJ, Le QT.
Oncogene.
2005;
24
(43):
6555-63
-
Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae.
Chen Y,
Feldman DE, Deng C, Brown JA, De Giacomo AF, Gaw AF, Shi G, Le QT, Brown JM, Koong AC.
Mol Cancer Res.
2005;
3
(12):
669-77
-
Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer.
Koong AC,
Christofferson E, Le QT, Goodman KA, Ho A, Kuo T, Ford JM, Fisher GA, Greco R, Norton J, Yang GP.
Int J Radiat Oncol Biol Phys.
2005;
63
(2):
320-3
-
Radiation dose reduction in four-dimensional computed tomography.
Li T,
Schreibmann E, Thorndyke B, Tillman G, Boyer A, Koong A, Goodman K, Xing L.
Med Phys.
2005;
32
(12):
3650-60
-
Identification of hypoxia regulated proteins in head and neck cancer by proteomic and tissue array profiling.
Chen,
et al.
Cancer Res.
2004;
64
(20):
7302-10
-
Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms.
Su CK,
Mehta V, Ravikumar L, Shah R, Pinto H, Halpern J, Koong A, Goffinet D, Le QT.
Int J Radiat Oncol Biol Phys.
2004;
60
(1):
171-7
-
Sample classification from protein mass spectrometry, by 'peak probability contrasts'.
Tibshirani R,
Hastie T, Narasimhan B, Soltys S, Shi G, Koong A, Le QT.
Bioinformatics.
2004;
20
(17):
3034-44
-
The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers.
Soltys SG,
Le QT, Shi G, Tibshirani R, Giaccia AJ, Koong AC.
Clin Cancer Res.
2004;
10
(14):
4806-12
-
Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients.
Le QT,
Kovacs MS, Dorie MJ, Koong A, Terris DJ, Pinto HA, Goffinet DR, Nowels K, Bloch D, Brown JM.
Int J Radiat Oncol Biol Phys.
2003;
56
(2):
375-83
-
Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas.
Le QT,
Sutphin PD, Raychaudhuri S, Yu SC, Terris DJ, Lin HS, Lum B, Pinto HA, Koong AC, Giaccia AJ.
Clin Cancer Res.
2003;
9
(1):
59-67
-
Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma.
Le QT,
Tate D, Koong A, Gibbs IC, Chang SD, Adler JR, Pinto HA, Terris DJ, Fee WE, Goffinet DR.
Int J Radiat Oncol Biol Phys.
2003;
56
(4):
1046-54
-
Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer.
Mehta VK,
Cho C, Ford JM, Jambalos C, Poen J, Koong A, Lin A, Bastidas JA, Young H, Dunphy EP, Fisher G.
Int J Radiat Oncol Biol Phys.
2003;
55
(1):
132-7
-
Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay.
Terris DJ,
Ho EY, Ibrahim HZ, Dorie MJ, Kovacs MS, Le QT, Koong AC, Pinto HA, Brown JM.
Arch Otolaryngol Head Neck Surg.
2002;
128
(6):
698-702
-
Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment.
Denko N,
Schindler C, Koong A, Laderoute K, Green C, Giaccia A.
Clin Cancer Res.
2000;
6
(2):
480-7
-
Analysis of HSF-1 phosphorylation in A549 cells treated with a variety of stresses.
Mivechi NF,
Koong AC, Giaccia AJ, Hahn GM.
Int J Hyperthermia.
1994 May-Jun;
10
(3):
371-9
-
Activators of protein kinase C selectively mediate cellular cytotoxicity to hypoxic cells and not aerobic cells.
Koong AC,
Chen EY, Kim CY, Giaccia AJ.
Int J Radiat Oncol Biol Phys.
1994;
29
(2):
259-65
-
Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.
Koong AC,
Chen EY, Giaccia AJ.
Cancer Res.
1994;
54
(6):
1425-30
-
Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2).
Koong AC,
Chen EY, Mivechi NF, Denko NC, Stambrook P, Giaccia AJ.
Cancer Res.
1994;
54
(20):
5273-9
-
Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction.
Koong AC,
Chen EY, Lee AS, Brown JM, Giaccia AJ.
Int J Radiat Oncol Biol Phys.
1994;
28
(3):
661-6
-
Modulation of potassium channels by protein tyrosine kinase inhibitors.
Saad AH,
Kuo SS, Koong AC, Hahn GM, Giaccia AJ.
J Cell Physiol.
1994;
161
(1):
142-8
-
The regulation of GRP78 and messenger RNA levels by hypoxia is modulated by protein kinase C activators and inhibitors.
Koong AC,
Auger EA, Chen EY, Giaccia AJ.
Radiat Res.
1994;
138
(1 Suppl):
S60-3
-
Activation of potassium channels by hypoxia and reoxygenation in the human lung adenocarcinoma cell line A549.
Koong AC,
Giaccia AJ, Hahn GM, Saad AH.
J Cell Physiol.
1993;
156
(2):
341-7
-
Potassium-channel activation in response to low doses of gamma-irradiation involves reactive oxygen intermediates in nonexcitatory cells.
Kuo SS,
Saad AH, Koong AC, Hahn GM, Giaccia AJ.
Proc Natl Acad Sci U S A.
1993;
90
(3):
908-12
-
Activation of the heat shock transcription factor by hypoxia in normal and tumor cell lines in vivo and in vitro.
Giaccia AJ,
Auger EA, Koong A, Terris DJ, Minchinton AI, Hahn GM, Brown JM.
Int J Radiat Oncol Biol Phys.
1992;
23
(4):
891-7
-
The influence of chronic anaemia on the radiosensitivity of two mouse tumours.
Koong AC,
Hirst DG.
Br J Cancer.
1991;
63
(4):
499-502
-
Therapeutic advantage of hypoxic cells in tumors: a theoretical study.
Brown JM,
Koong A.
J Natl Cancer Inst.
1991;
83
(3):
178-85
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