Publications
-
In silico genetics: identification of a functional element regulating H2-Ealpha gene expression.
Liao G,
Wang J, Guo J, Allard J, Cheng J, Ng A, Shafer S, Puech A, McPherson JD, Foernzler D, Peltz G, Usuka J.
Science.
2004;
306
(5696):
690-5
-
Mixed-effects modeling of the intrinsic ventilatory depressant potency of propofol in the non-steady state.
Bouillon T,
Bruhn J, Radu-Radulescu L, Andresen C, Cohane C, Shafer SL.
Anesthesiology.
2004;
100
(2):
240-50
-
Pharmacodynamic interaction between propofol and remifentanil regarding hypnosis, tolerance of laryngoscopy, bispectral index, and electroencephalographic approximate entropy.
Bouillon TW,
Bruhn J, Radulescu L, Andresen C, Shafer TJ, Cohane C, Shafer SL.
Anesthesiology.
2004;
100
(6):
1353-72
-
A model of the ventilatory depressant potency of remifentanil in the non-steady state.
Bouillon T,
Bruhn J, Radu-Radulescu L, Andresen C, Cohane C, Shafer SL.
Anesthesiology.
2003;
99
(4):
779-87
-
Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics.
Minto CF,
Schnider TW, Gregg KM, Henthorn TK, Shafer SL.
Anesthesiology.
2003;
99
(2):
324-33
-
Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic model.
Barr J,
Egan TD, Sandoval NF, Zomorodi K, Cohane C, Gambus PL, Shafer SL.
Anesthesiology.
2001;
95
(2):
324-33
-
Response surface model for anesthetic drug interactions.
Minto CF,
Schnider TW, Short TG, Gregg KM, Gentilini A, Shafer SL.
Anesthesiology.
2000;
92
(6):
1603-16
-
The influence of age on propofol pharmacodynamics.
Schnider TW,
Minto CF, Shafer SL, Gambus PL, Andresen C, Goodale DB, Youngs EJ.
Anesthesiology.
1999;
90
(6):
1502-16
-
Cerebrospinal fluid pharmacokinetics and pharmacodynamics of intrathecal neostigmine methylsulfate in humans.
Shafer SL,
Eisenach JC, Hood DD, Tong C.
Anesthesiology.
1998;
89
(5):
1074-88
-
Population pharmacodynamics of midazolam administered by target controlled infusion in SICU patients after CABG surgery.
Somma J,
Donner A, Zomorodi K, Sladen R, Ramsay J, Geller E, Shafer SL.
Anesthesiology.
1998;
89
(6):
1430-43
-
Population pharmacokinetics of midazolam administered by target controlled infusion for sedation following coronary artery bypass grafting.
Zomorodi K,
Donner A, Somma J, Barr J, Sladen R, Ramsay J, Geller E, Shafer SL.
Anesthesiology.
1998;
89
(6):
1418-29
-
The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers.
Schnider TW,
Minto CF, Gambus PL, Andresen C, Goodale DB, Shafer SL, Youngs EJ.
Anesthesiology.
1998;
88
(5):
1170-82
-
Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development.
Minto CF,
Schnider TW, Egan TD, Youngs E, Lemmens HJ, Gambus PL, Billard V, Hoke JF, Moore KH, Hermann DJ, Muir KT, Mandema JW, Shafer SL.
Anesthesiology.
1997;
86
(1):
10-23
-
Pharmacokinetics and pharmacodynamics of remifentanil. II. Model application.
Minto CF,
Schnider TW, Shafer SL.
Anesthesiology.
1997;
86
(1):
24-33
-
Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers.
Egan TD,
Minto CF, Hermann DJ, Barr J, Muir KT, Shafer SL.
Anesthesiology.
1996;
84
(4):
821-33
-
Computer-controlled epidural infusion to targeted cerebrospinal fluid concentrations in humans. Clonidine.
Eisenach JC,
Hood DD, Tuttle R, Shafer S, Smith T, Tong C.
Anesthesiology.
1995;
83
(1):
33-47
-
Linearity of pharmacokinetics and model estimation of sufentanil.
Gepts E,
Shafer SL, Camu F, Stanski DR, Woestenborghs R, Van Peer A, Heykants JJ.
Anesthesiology.
1995;
83
(6):
1194-204
-
The pharmacokinetics of propofol in children using three different data analysis approaches.
Kataria BK,
Ved SA, Nicodemus HF, Hoy GR, Lea D, Dubois MY, Mandema JW, Shafer SL.
Anesthesiology.
1994;
80
(1):
104-22
-
The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers.
Egan TD,
Lemmens HJ, Fiset P, Hermann DJ, Muir KT, Stanski DR, Shafer SL.
Anesthesiology.
1993;
79
(5):
881-92
-
Algorithms to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump.
Shafer SL,
Gregg KM.
J Pharmacokinet Biopharm.
1992;
20
(2):
147-69
-
Application of semilinear canonical correlation to the measurement of opioid drug effect.
Gregg KM,
Varvel JR, Shafer SL.
J Pharmacokinet Biopharm.
1992;
20
(6):
611-35
-
Measuring the predictive performance of computer-controlled infusion pumps.
Varvel JR,
Donoho DL, Shafer SL.
J Pharmacokinet Biopharm.
1992;
20
(1):
63-94
-
Pharmacokinetics, pharmacodynamics, and rational opioid selection.
Shafer SL,
Varvel JR.
Anesthesiology.
1991;
74
(1):
53-63
-
Pharmacokinetics of fentanyl administered by computer-controlled infusion pump.
Shafer SL,
Varvel JR, Aziz N, Scott JC.
Anesthesiology.
1990;
73
(6):
1091-102
-
The prospective use of population pharmacokinetics in a computer-driven infusion system for alfentanil.
Raemer DB,
Buschman A, Varvel JR, Philip BK, Johnson MD, Stein DA, Shafer SL.
Anesthesiology.
1990;
73
(1):
66-72
-
Absorption characteristics of transdermally administered fentanyl.
Varvel JR,
Shafer SL, Hwang SS, Coen PA, Stanski DR.
Anesthesiology.
1989;
70
(6):
928-34
-
Influence of administration rate on propofol plasma-effect site equilibration.
Struys MM,
Coppens MJ, De Neve N, Mortier EP, Doufas AG, Van Bocxlaer JF, Shafer SL.
Anesthesiology.
2007;
107
(3):
386-96
-
A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children.
Petroz GC,
Sikich N, James M, van Dyk H, Shafer SL, Schily M, Lerman J.
Anesthesiology.
2006;
105
(6):
1098-110
-
Arterial and venous pharmacokinetics of ropivacaine with and without epinephrine after thoracic paravertebral block.
Karmakar MK,
Ho AM, Law BK, Wong AS, Shafer SL, Gin T.
Anesthesiology.
2005;
103
(4):
704-11
-
Differential activation of trigeminal C or Adelta nociceptors by infrared diode laser in rats: behavioral evidence.
Tzabazis A,
Klyukinov M, Manering N, Nemenov MI, Shafer SL, Yeomans DC.
Brain Res.
2005;
1037
(1-2):
148-56
-
Pharmacogenomics and drug development.
Guo Y,
Shafer S, Weller P, Usuka J, Peltz G.
Pharmacogenomics.
2005;
6
(8):
857-64
-
Variability of target-controlled infusion is less than the variability after bolus injection.
Hu C,
Horstman DJ, Shafer SL.
Anesthesiology.
2005;
102
(3):
639-45
-
Application of Bispectral Index and Narcotrend index to the measurement of the electroencephalographic effects of isoflurane with and without burst suppression.
Kreuer S,
Bruhn J, Larsen R, Grundmann U, Shafer SL, Wilhelm W.
Anesthesiology.
2004;
101
(4):
847-54
-
Determination of the pharmacodynamic interaction of propofol and remifentanil during esophagogastroduodenoscopy in children.
Drover DR,
Litalien C, Wellis V, Shafer SL, Hammer GB.
Anesthesiology.
2004;
100
(6):
1382-6
-
Induction speed is not a determinant of propofol pharmacodynamics.
Doufas AG,
Bakhshandeh M, Bjorksten AR, Shafer SL, Sessler DI.
Anesthesiology.
2004;
101
(5):
1112-21
-
Picking safe combinations.
Shafer SL,
Anesthesiology.
2004;
101
(6):
1260-1
-
Shock values.
Shafer SL,
Anesthesiology.
2004;
101
(3):
567-8
-
Spectral entropy as an electroencephalographic measure of anesthetic drug effect: a comparison with bispectral index and processed midlatency auditory evoked response.
Vanluchene AL,
Vereecke H, Thas O, Mortier EP, Shafer SL, Struys MM.
Anesthesiology.
2004;
101
(1):
34-42
-
Target controlled infusions: targeting the effect site while limiting peak plasma concentration.
Van Poucke GE,
Bravo LJ, Shafer SL.
IEEE Trans Biomed Eng.
2004;
51
(11):
1869-75
-
Teaching application of clinical pharmacology skills using unusual observations from clozapine overdoses.
Pollak PT,
Shafer SL.
J Clin Pharmacol.
2004;
44
(2):
141-9
-
Use of population modeling to define rational monitoring of amiodarone hepatic effects.
Pollak PT,
Shafer SL.
Clin Pharmacol Ther.
2004;
75
(4):
342-51
-
Cephalad movement of morphine and fentanyl in humans after intrathecal injection.
Eisenach JC,
Hood DD, Curry R, Shafer SL.
Anesthesiology.
2003;
99
(1):
166-73
-
Correlation of approximate entropy, bispectral index, and spectral edge frequency 95 (SEF95) with clinical signs of "anesthetic depth" during coadministration of propofol and remifentanil.
Bruhn J,
Bouillon TW, Radulescu L, Hoeft A, Bertaccini E, Shafer SL.
Anesthesiology.
2003;
98
(3):
621-7
-
Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone.
Eger EI,
Xing Y, Pearce R, Shafer S, Laster MJ, Zhang Y, Fanselow MS, Sonner JM.
Anesth Analg.
2003;
96
(4):
1010-8, table of contents
-
MAC Attack?
Sani O,
Shafer SL.
Anesthesiology.
2003;
99
(6):
1249-50
-
Mathematical analysis of a pharmacodynamic model without plasma concentrations to extend its applicability.
Nava-Ocampo AA,
Shafer SL, Velázquez-Armenta Y, Ruiz-Velazco S, Toni B.
Med Hypotheses.
2003;
60
(3):
453-7
-
Piritramide and alfentanil display similar respiratory depressant potency.
Bouillon T,
Garstka G, Stafforst D, Shafer S, Schwilden H, Hoeft A.
Acta Anaesthesiol Scand.
2003;
47
(10):
1231-41
-
Target-controlled infusions for intravenous anesthetics: surfing USA not!
Egan TD,
Shafer SL.
Anesthesiology.
2003;
99
(5):
1039-41
-
Artifact robustness, inter- and intraindividual baseline stability, and rational EEG parameter selection.
Bruhn J,
Bouillon TW, Hoeft A, Shafer SL.
Anesthesiology.
2002;
96
(1):
54-9
-
Efficient trial design for eliciting a pharmacokinetic-pharmacodynamic model-based response surface describing the interaction between two intravenous anesthetic drugs.
Short TG,
Ho TY, Minto CF, Schnider TW, Shafer SL.
Anesthesiology.
2002;
96
(2):
400-8
-
Non-steady state analysis of the pharmacokinetic interaction between propofol and remifentanil.
Bouillon T,
Bruhn J, Radu-Radulescu L, Bertaccini E, Park S, Shafer S.
Anesthesiology.
2002;
97
(6):
1350-62
-
Pharmacokinetic study of FFP photochemically treated with amotosalen (S-59) and UV light compared to FFP in healthy volunteers anticoagulated with warfarin.
Hambleton J,
Wages D, Radu-Radulescu L, Adams M, MacKenzie M, Shafer S, Lee M, Smyers J, Wiesehahn G, Corash L.
Transfusion.
2002;
42
(10):
1302-7
-
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model.
Barr J,
Zomorodi K, Bertaccini EJ, Shafer SL, Geller E.
Anesthesiology.
2001;
95
(2):
286-98
-
Onset of propofol-induced burst suppression may be correctly detected as deepening of anaesthesia by approximate entropy but not by bispectral index.
Bruhn J,
Bouillon TW, Shafer SL.
Br J Anaesth.
2001;
87
(3):
505-7
-
Bispectral index (BIS) and burst suppression: revealing a part of the BIS algorithm.
Bruhn J,
Bouillon TW, Shafer SL.
J Clin Monit Comput.
2000;
16
(8):
593-6
-
Characterization of benzodiazepine receptors in the cerebellum.
Lameh J,
Wang P, Meredith D, Shafer SL, Loew GH.
Prog Neuropsychopharmacol Biol Psychiatry.
2000;
24
(6):
979-91
-
Comparison of plasma compartment versus two methods for effect compartment--controlled target-controlled infusion for propofol.
Struys MM,
De Smet T, Depoorter B, Versichelen LF, Mortier EP, Dumortier FJ, Shafer SL, Rolly G.
Anesthesiology.
2000;
92
(2):
399-406
-
Electromyographic activity falsely elevates the bispectral index.
Bruhn J,
Bouillon TW, Shafer SL.
Anesthesiology.
2000;
92
(5):
1485-7
-
Hot air or full steam ahead? An empirical pharmacokinetic model of potent inhalational agents.
Bouillon T,
Shafer SL.
Br J Anaesth.
2000;
84
(4):
429-31
-
Location, location, location.
Shafer SL,
Eisenach JC.
Anesthesiology.
2000;
92
(3):
641-3
-
Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers.
Dershwitz M,
Walsh JL, Morishige RJ, Connors PM, Rubsamen RM, Shafer SL, Rosow CE.
Anesthesiology.
2000;
93
(3):
619-28
-
Population pharmacokinetics of long-term oral amiodarone therapy.
Pollak PT,
Bouillon T, Shafer SL.
Clin Pharmacol Ther.
2000;
67
(6):
642-52
-
The pharmacology of anesthetic drugs in elderly patients.
Shafer SL,
Anesthesiol Clin North America.
2000;
18
(1):
1-29, v
-
Unraveling the identity of benzodiazepine binding sites in rat hipppocampus and olfactory bulb.
Lameh J,
Wang P, Elgart D, Meredith D, Shafer SL, Loew GH.
Eur J Pharmacol.
2000;
400
(2-3):
167-76
-
Drug interactions. Applications in fast-track anesthesia.
Shafer SL,
Acta Anaesthesiol Belg.
1999;
50
(4):
153-60
-
Does size matter?
Bouillon T,
Shafer SL.
Anesthesiology.
1998;
89
(3):
557-60
-
Pharmacokinetics and pharmacodynamics in anesthetic drug development.
Shafer SL,
Acta Anaesthesiol Belg.
1998;
49
(2):
65-78
-
Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers.
Gambús PL,
Schnider TW, Minto CF, Youngs EJ, Billard V, Brose WG, Hochhaus G, Shafer SL.
Clin Pharmacol Ther.
1998;
64
(1):
27-38
-
Pharmacokinetics, cortisol release, and hemodynamics after intravenous and subcutaneous injection of human corticotropin-releasing factor in humans.
Angst MS,
Dyck JB, Azarnoff DL, Goldblum R, Ho B, Gfroerer T, Linton EA, Glynn BP, Shafer SL.
Clin Pharmacol Ther.
1998;
64
(5):
499-510
-
Writing successful research proposals for medical science.
Schwinn DA,
DeLong ER, Shafer SL.
Anesthesiology.
1998;
88
(6):
1660-6
-
A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect.
Billard V,
Gambus PL, Chamoun N, Stanski DR, Shafer SL.
Clin Pharmacol Ther.
1997;
61
(1):
45-58
-
Nomenclature for computer-assisted infusion devices.
Glass PS,
Glen JB, Kenny GN, Schüttler J, Shafer SL.
Anesthesiology.
1997;
86
(6):
1430-1
-
Urine and plasma catecholamine and cortisol concentrations after myocardial revascularization. Modulation by continuous sedation. Multicenter Study of Perioperative Ischemia (McSPI) Research Group, and the Ischemia Research and Education Foundation (IREF).
Plunkett JJ,
Reeves JD, Ngo L, Bellows W, Shafer SL, Roach G, Howse J, Herskowitz A, Mangano DT.
Anesthesiology.
1997;
86
(4):
785-96
-
Comparative absorption kinetics of intramuscular midazolam and diazepam.
Hung OR,
Dyck JB, Varvel J, Shafer SL, Stanski DR.
Can J Anaesth.
1996;
43
(5 Pt 1):
450-5
-
Derivation and cross-validation of pharmacokinetic parameters for computer-controlled infusion of lidocaine in pain therapy.
Schnider TW,
Gaeta R, Brose W, Minto CF, Gregg KM, Shafer SL.
Anesthesiology.
1996;
84
(5):
1043-50
-
Inhalation versus intravenous anesthesia: a fictitious debate between E.I. Eger II and P.F. White.
Shafer SL,
Gambús PL.
J Clin Anesth.
1996;
8
(3 Suppl):
38S-41S
-
Pharmacokinetic model-driven infusion of fentanyl in children.
Ginsberg B,
Howell S, Glass PS, Margolis JO, Ross AK, Dear GL, Shafer SL.
Anesthesiology.
1996;
85
(6):
1268-75
-
Pharmacokinetics of propofol in adult patients undergoing coronary revascularization. The Multicenter Study of Perioperative Ischemia Research Group.
Bailey JM,
Mora CT, Shafer SL.
Anesthesiology.
1996;
84
(6):
1288-97
-
Semilinear canonical correlation applied to the measurement of the electroencephalographic effects of midazolam and flumazenil reversal.
Schnider TW,
Minto CF, Fiset P, Gregg KM, Shafer SL.
Anesthesiology.
1996;
84
(3):
510-9
-
Allometry of pharmacokinetics and pharmacodynamics of the muscle relaxant metocurine in mammals.
Gronert GA,
Fung DL, Jones JH, Shafer SL, Hildebrand SV, Disbrow EA.
Am J Physiol.
1995;
268
(1 Pt 2):
R85-91
-
Biopharmaceutics of a new transdermal fentanyl device.
Fiset P,
Cohane C, Browne S, Brand SC, Shafer SL.
Anesthesiology.
1995;
83
(3):
459-69
-
Clinical drug level predictions and practice.
Howell S,
Shafer SL, Reves JG, Sladen R.
Int Anesthesiol Clin.
1995;
33
(3):
91-100
-
Evolving clinically useful predictors of recovery from intravenous anesthetics.
Schnider TW,
Shafer SL.
Anesthesiology.
1995;
83
(5):
902-5
-
Pharmacodynamic modeling of the electroencephalographic effects of flumazenil in healthy volunteers sedated with midazolam.
Fiset P,
Lemmens HL, Egan TD, Shafer SL, Stanski DR, Egan TE.
Clin Pharmacol Ther.
1995;
58
(5):
567-82
-
Pharmacokinetics of computer-controlled alfentanil administration in children undergoing cardiac surgery.
Fiset P,
Mathers L, Engstrom R, Fitzgerald D, Brand SC, Hsu F, Shafer SL.
Anesthesiology.
1995;
83
(5):
944-55
-
Pharmacokinetics of inhaled liposome-encapsulated fentanyl.
Hung OR,
Whynot SC, Varvel JR, Shafer SL, Mezei M.
Anesthesiology.
1995;
83
(2):
277-84
-
Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats.
Chaplan SR,
Bach FW, Shafer SL, Yaksh TL.
Anesthesiology.
1995;
83
(4):
775-85
-
Quantifying anesthetic drug interaction. Implications for drug dosing.
Stanski DR,
Shafer SL.
Anesthesiology.
1995;
83
(1):
1-5
-
The pharmacokinetics of 8-methoxypsoralen following i.v. administration in humans.
Billard V,
Gambus PL, Barr J, Minto CF, Corash L, Tessman JW, Stickney JL, Shafer SL.
Br J Clin Pharmacol.
1995;
40
(4):
347-60
-
Validation of the alfentanil canonical univariate parameter as a measure of opioid effect on the electroencephalogram.
Gambús PL,
Gregg KM, Shafer SL.
Anesthesiology.
1995;
83
(4):
747-56
-
An efficient control strategy for dosage regimens.
Hu C,
Lovejoy WS, Shafer SL.
J Pharmacokinet Biopharm.
1994;
22
(1):
73-94
-
Comparison of some control strategies for three-compartment PK/PD models.
Hu C,
Lovejoy WS, Shafer SL.
J Pharmacokinet Biopharm.
1994;
22
(6):
525-50
-
Pharmacokinetic parameters relevant to recovery from opioids.
Youngs EJ,
Shafer SL.
Anesthesiology.
1994;
81
(4):
833-42
-
Pharmacokinetic-pharmacodynamic modeling in drug development: application to the investigational opioid trefentanil.
Lemmens HJ,
Dyck JB, Shafer SL, Stanski DR.
Clin Pharmacol Ther.
1994;
56
(3):
261-71
-
Pharmacokinetics and pharmacodynamics of intraspinal dexmedetomidine in sheep.
Eisenach JC,
Shafer SL, Bucklin BA, Jackson C, Kallio A.
Anesthesiology.
1994;
80
(6):
1349-59
-
Cardiopulmonary and behavioral responses to computer-driven infusion of detomidine in standing horses.
Daunt DA,
Dunlop CI, Chapman PL, Shafer SL, Ruskoaho H, Vakkuri O, Hodgson DS, Tyler LM, Maze M.
Am J Vet Res.
1993;
54
(12):
2075-82
-
Computer-controlled infusion of intravenous dexmedetomidine hydrochloride in adult human volunteers.
Dyck JB,
Maze M, Haack C, Azarnoff DL, Vuorilehto L, Shafer SL.
Anesthesiology.
1993;
78
(5):
821-8
-
Constant versus optimal plasma concentrations.
Shafer SL,
Anesth Analg.
1993;
76
(3):
467-9
-
Dexmedetomidine decreases cerebral blood flow velocity in humans.
Zornow MH,
Maze M, Dyck JB, Shafer SL.
J Cereb Blood Flow Metab.
1993;
13
(2):
350-3
-
The pharmacokinetics and hemodynamic effects of intravenous and intramuscular dexmedetomidine hydrochloride in adult human volunteers.
Dyck JB,
Maze M, Haack C, Vuorilehto L, Shafer SL.
Anesthesiology.
1993;
78
(5):
813-20
-
Improving the clinical utility of anesthetic drug pharmacokinetics.
Shafer SL,
Stanski DR.
Anesthesiology.
1992;
76
(3):
327-30
-
Plasma concentration clamping in the rat using a computer-controlled infusion pump.
Gustafsson LL,
Ebling WF, Osaki E, Harapat S, Stanski DR, Shafer SL.
Pharm Res.
1992;
9
(6):
800-7
-
Thiopental pharmacodynamics. I. Defining the pseudo-steady-state serum concentration-EEG effect relationship.
Bührer M,
Maitre PO, Hung OR, Ebling WF, Shafer SL, Stanski DR.
Anesthesiology.
1992;
77
(2):
226-36
-
Thiopental pharmacodynamics. II. Quantitation of clinical and electroencephalographic depth of anesthesia.
Hung OR,
Varvel JR, Shafer SL, Stanski DR.
Anesthesiology.
1992;
77
(2):
237-44
-
A simple analytical solution to the three-compartment pharmacokinetic model suitable for computer-controlled infusion pumps.
Bailey JM,
Shafer SL.
IEEE Trans Biomed Eng.
1991;
38
(6):
522-5
-
A simple pocket calculator approach to predict anesthetic drug concentrations from pharmacokinetic data.
Maitre PO,
Shafer SL.
Anesthesiology.
1990;
73
(2):
332-6
-
Estimating the rate of thiopental blood-brain equilibration using pseudo steady state serum concentrations.
Maitre PO,
Bührer M, Shafer SL, Stanski DR.
J Pharmacokinet Biopharm.
1990;
18
(3):
175-87
-
Quantitation of thiopental anesthetic depth with clinical stimuli.
Hung OR,
Varvel J, Shafer S, Stanski DR.
Can J Anaesth.
1990;
37
(4 Pt 2):
S18
-
Two equally valid interpretations of the linear multicompartment mammillary pharmacokinetic model.
Jacobs JR,
Shafer SL, Larsen JL, Hawkins ED.
J Pharm Sci.
1990;
79
(4):
331-3
-
A comparison of parametric with semiparametric analysis of the concentration versus effect relationship of metocurine in dogs and pigs.
Shafer SL,
Varvel JR, Gronert GA.
J Pharmacokinet Biopharm.
1989;
17
(3):
291-304
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Exercise produces sensitivity to metocurine.
Gronert GA,
White DA, Shafer SL, Matteo RS.
Anesthesiology.
1989;
70
(6):
973-7
-
The longitudinal distribution of pulmonary vascular resistance during unilateral hypoxia.
Siegel LC,
Pearl RG, Shafer SL, Ream AK, Prielipp RC.
Anesthesiology.
1989;
70
(3):
527-32
-
Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia.
Shafer A,
Doze VA, Shafer SL, White PF.
Anesthesiology.
1988;
69
(3):
348-56
-
Testing computer-controlled infusion pumps by simulation.
Shafer SL,
Siegel LC, Cooke JE, Scott JC.
Anesthesiology.
1988;
68
(2):
261-6
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