Publications
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Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth.
Hilgendorff A,
Parai K, Ertsey R, Juliana Rey-Parra G, Thébaud B, Tamosiuniene R, Jain N, Navarro EF, Starcher BC, Nicolls MR, Rabinovitch M, Bland RD.
Am J Physiol Lung Cell Mol Physiol.
2012;
303
(3):
L215-27
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Inhibiting lung elastase activity enables lung growth in mechanically ventilated newborn mice.
Hilgendorff A,
Parai K, Ertsey R, Jain N, Navarro EF, Peterson JL, Tamosiuniene R, Nicolls MR, Starcher BC, Rabinovitch M, Bland RD.
Am J Respir Crit Care Med.
2011;
184
(5):
537-46
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Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice.
Mokres LM,
Parai K, Hilgendorff A, Ertsey R, Alvira CM, Rabinovitch M, Bland RD.
Am J Physiol Lung Cell Mol Physiol.
2010;
298
(1):
L23-35
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Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice
Bland, RD,
Ertsey R, Mokres LM, Xu L, Jacobson BE, Jiang S, Alvira CM, Rabinovitch M, Shinwell ES and Dixit A.
Am J Physiol Lung Cell Mol Physiol.
2008;
294
(1):
L3-L14
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Dysregulation of pulmonary elastin synthesis and assembly in preterm lambs with chronic lung disease.
Bland RD,
Xu L, Ertsey R, Rabinovitch M, Albertine KH, Wynn KA, Kumar VH, Ryan RM, Swartz DD, Csiszar K, Fong KS.
Am J Physiol Lung Cell Mol Physiol.
2007;
292
(6):
L1370-84
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Mechanical ventilation with 40% oxygen reduces pulmonary expression of genes that regulate lung development and impairs alveolar septation in newborn mice.
Bland RD,
Mokres LM, Ertsey R, Jacobson BE, Jiang S, Rabinovitch M, Xu L, Shinwell ES, Zhang F, Beasley MA.
Am J Physiol Lung Cell Mol Physiol.
2007;
293
(5):
L1099-110
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Inhaled nitric oxide effects on lung structure and function in chronically ventilated preterm lambs
Bland RD,
Albertine KH, Carlton DP, MacRitchie AN.
Am J Respir Crit Care Med.
2005;
172
(7):
899-906
-
Neonatal chronic lung disease in the post-surfactant era.
Bland RD,
Biol Neonate.
2005;
88
(3):
181-91
-
Pulmonary vascular dysfunction in preterm lambs with chronic lung disease.
Bland RD,
Ling CY, Albertine KH, Carlton DP, MacRitchie AJ, Day RW, Dahl MJ.
Am J Physiol Lung Cell Mol Physiol.
2003;
285
(1):
L76-85
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Reduced endothelial nitric oxide synthase in lungs of chronically ventilated preterm lambs.
MacRitchie AN,
Albertine KH, Sun J, Lei PS, Jensen SC, Freestone AA, Clair PM, Dahl MJ, Godfrey EA, Carlton DP, Bland RD.
Am J Physiol Lung Cell Mol Physiol.
2001;
281
(4):
L1011-20
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Chronic lung injury in preterm lambs: abnormalities of the pulmonary circulation and lung fluid balance.
Bland RD,
Albertine KH, Carlton DP, Kullama L, Davis P, Cho SC, Kim BI, Dahl M, Tabatabaei N.
Pediatr Res.
2000;
48
(1):
64-74
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Chronic lung injury in preterm lambs. Disordered respiratory tract development.
Albertine KH,
Jones GP, Starcher BC, Bohnsack JF, Davis PL, Cho SC, Carlton DP, Bland RD.
Am J Respir Crit Care Med.
1999;
159
(3):
945-58
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Chronic lung injury in preterm lambs: disordered pulmonary elastin deposition.
Pierce RA,
Albertine KH, Starcher BC, Bohnsack JF, Carlton DP, Bland RD.
Am J Physiol.
1997;
272
(3 Pt 1):
L452-60
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Molecular determinants of lung development.
Morrisey EE,
Cardoso WV, Lane RH, Rabinovitch M, Abman SH, Ai X, Albertine KH, Bland RD, Chapman HA, Checkley W, Epstein JA, Kintner CR, Kumar M, Minoo P, Mariani TJ, McDonald DM, Mukouyama YS, Prince LS, Reese J, Rossant J, Shi W, Sun X, Werb Z, Whitsett JA, Gail D, Blaisdell CJ, Lin QS.
Ann Am Thorac Soc.
2013;
10
(2):
S12-6
-
Chronic lung disease in preterm lambs: effect of daily vitamin A treatment on alveolarization.
Albertine KH,
Dahl MJ, Gonzales LW, Wang ZM, Metcalfe D, Hyde DM, Plopper CG, Starcher BC, Carlton DP, Bland RD.
Am J Physiol Lung Cell Mol Physiol.
2010;
299
(1):
L59-72
-
Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
Rey-Parra GJ,
Archer SL, Bland RD, Albertine KH, Carlton DP, Cho SC, Kirby B, Haromy A, Eaton F, Wu X, Thébaud B.
Am J Respir Crit Care Med.
2008;
178
(4):
399-406
-
Impaired alveolar development and abnormal lung elastin in preterm lambs with chronic lung injury: potential benefits of retinol treatment.
Bland RD,
Albertine KH, Pierce RA, Starcher BC, Carlton DP.
Biol Neonate.
2003;
84
(1):
101-2
-
Loss of liquid from the lung lumen in labor: more than a simple "squeeze".
Bland RD,
Am J Physiol Lung Cell Mol Physiol.
2001;
280
(4):
L602-5
-
Inhaled nitric oxide: a premature remedy for chronic lung disease?
Bland RD,
Pediatrics.
1999;
103
(3):
667-70
-
Altered vascular development in preterm lambs with chronic lung injury.
Albertine KH,
MacRitchie AN, Young BJ, Cho SC, Kullama LK, Carlton DP, Bland RD.
Chest.
1998;
114
(1 Suppl):
6S-7S
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Role of neutrophils in lung vascular injury and edema after premature birth in lambs.
Carlton DP,
Albertine KH, Cho SC, Lont M, Bland RD.
J Appl Physiol.
1997;
83
(4):
1307-17
-
Retrovirus-mediated gene transfer in lungs of living fetal sheep.
Pitt BR,
Schwarz MA, Pilewski JM, Nakayama D, Mueller GM, Robbins PD, Watkins SA, Albertine KH, Bland RD.
Gene Ther.
1995;
2
(5):
344-50
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Surfactant treatment at birth reduces lung vascular injury and edema in preterm lambs.
Carlton DP,
Cho SC, Davis P, Lont M, Bland RD.
Pediatr Res.
1995;
37
(3):
265-70
-
Vasopressin effects on lung liquid volume in fetal sheep.
Cummings JJ,
Carlton DP, Poulain FR, Fike CD, Keil LC, Bland RD.
Pediatr Res.
1995;
38
(1):
30-5
-
Changes in lung lipid during spontaneous labor in fetal sheep.
Chapman DL,
Carlton DP, Nielson DW, Cummings JJ, Poulain FR, Bland RD.
J Appl Physiol.
1994;
76
(2):
523-30
-
Inflation pressure and lung vascular injury in preterm lambs.
Carlton DP,
Cho SC, Davis P, Bland RD.
Chest.
1994;
105
(3 Suppl):
115S-116S
-
Lung vascular protein permeability in preterm fetal and mature newborn sheep.
Carlton DP,
Cummings JJ, Scheerer RG, Bland RD.
J Appl Physiol.
1994;
77
(2):
782-8
-
Hypoproteinemia slows lung liquid clearance in young lambs.
Cummings JJ,
Carlton DP, Poulain FR, Raj JU, Bland RD.
J Appl Physiol.
1993;
74
(1):
153-60
-
Developmental changes in lung epithelial ion transport and liquid movement.
Bland RD,
Nielson DW.
Annu Rev Physiol.
1992:
54
373-94
-
Increased pulmonary vascular filtration pressure does not alter lung liquid secretion in fetal sheep.
Carlton DP,
Cummings JJ, Poulain FR, Bland RD.
J Appl Physiol.
1992;
72
(2):
650-5
-
Ion transport regulation of lung liquid secretion in foetal lambs.
Carlton DP,
Cummings JJ, Chapman DL, Poulain FR, Bland RD.
J Dev Physiol.
1992;
17
(2):
99-107
-
Developmental changes in pleural liquid protein concentration in sheep.
Broaddus VC,
Araya M, Carlton DP, Bland RD.
Am Rev Respir Dis.
1991;
143
(1):
38-41
-
Intrapulmonary terbutaline and aminophylline decrease lung liquid in fetal lambs.
Chapman DL,
Carlton DP, Cummings JJ, Poulain FR, Bland RD.
Pediatr Res.
1991;
29
(4 Pt 1):
357-61
-
Pathophysiology of neonatal lung injury.
Bland RD,
Int J Technol Assess Health Care.
1991:
7 Suppl 1
56-60
-
Developmental differences in rabbit lung epithelial cell Na(+)-K(+)-ATPase.
Chapman DL,
Widdicombe JH, Bland RD.
Am J Physiol.
1990;
259
(6 Pt 1):
L481-7
-
Lung epithelial ion transport and fluid movement during the perinatal period.
Bland RD,
Am J Physiol.
1990;
259
(2 Pt 1):
L30-7
-
Lung overexpansion increases pulmonary microvascular protein permeability in young lambs.
Carlton DP,
Cummings JJ, Scheerer RG, Poulain FR, Bland RD.
J Appl Physiol.
1990;
69
(2):
577-83
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Furosemide reduces lung fluid filtration in lambs with lung microvascular injury from air emboli.
Berner ME,
Teague WG, Scheerer RG, Bland RD.
J Appl Physiol.
1989;
67
(5):
1990-6
-
Lung fluid balance in lambs before and after premature birth.
Bland RD,
Carlton DP, Scheerer RG, Cummings JJ, Chapman DL.
J Clin Invest.
1989;
84
(2):
568-76
-
Alveolar liquid pressures in newborn and adult rabbit lungs.
Fike CD,
Lai-Fook SJ, Bland RD.
J Appl Physiol.
1988;
64
(4):
1629-35
-
Effect of hypoxia on lung lymph flow in newborn lambs with left atrial hypertension.
Raj JU,
Hazinski TA, Bland RD.
Am J Physiol.
1988;
254
(3 Pt 2):
H487-93
-
Effect of pulmonary perfusion on lung fluid filtration in young lambs.
Teague WG,
Berner ME, Bland RD.
Am J Physiol.
1988;
255
(6 Pt 2):
H1336-41
-
Lung liquid clearance before and after birth.
Bland RD,
Semin Perinatol.
1988;
12
(2):
124-33
-
Microvascular pressures during hypoxia in isolated lungs of newborn rabbits.
Fike CD,
Lai-Fook SJ, Bland RD.
J Appl Physiol.
1988;
65
(1):
283-7
-
Lung vascular effects of lipid infusion in awake lambs.
Teague WG,
Raj JU, Braun D, Berner ME, Clyman RI, Bland RD.
Pediatr Res.
1987;
22
(6):
714-9
-
Microvascular pressures measured by micropuncture in lungs of newborn rabbits.
Fike CD,
Lai-Fook SJ, Bland RD.
J Appl Physiol.
1987;
63
(3):
1070-5
-
Pathogenesis of pulmonary edema after premature birth.
Bland RD,
Adv Pediatr.
1987:
34
175-221
-
Cation transport in lung epithelial cells derived from fetal, newborn, and adult rabbits.
Bland RD,
Boyd CA.
J Appl Physiol.
1986;
61
(2):
507-15
-
Effect of hypoproteinemia on lung fluid balance in awake newborn lambs.
Hazinski TA,
Bland RD, Hansen TN, Sedin EG, Goldberg RB.
J Appl Physiol.
1986;
61
(3):
1139-48
-
Lung luminal liquid clearance in newborn lambs. Effect of pulmonary microvascular pressure elevation.
Raj JU,
Bland RD.
Am Rev Respir Dis.
1986;
134
(2):
305-10
-
Microvascular pressures measured by micropipettes in isolated edematous rabbit lungs.
Raj JU,
Bland RD, Lai-Fook SJ.
J Appl Physiol.
1986;
60
(2):
539-45
-
Oxygen-induced lung microvascular injury in neutropenic rabbits and lambs.
Raj JU,
Hazinski TA, Bland RD.
J Appl Physiol.
1985;
58
(3):
921-7
-
Effects of asphyxia on lung fluid balance in baby lambs.
Hansen TN,
Hazinski TA, Bland RD.
J Clin Invest.
1984;
74
(2):
370-6
-
Lung fluid balance in hypoxic lambs.
Hansen TN,
Haberkern CM, Hazinski TA, Bland RD.
Pediatr Res.
1984;
18
(5):
434-40
-
Dynamics of pulmonary water before and after birth.
Bland RD,
Acta Paediatr Scand Suppl.
1983:
305
12-20
-
Edema formation in the lungs and its relationship to neonatal respiratory distress.
Bland RD,
Acta Paediatr Scand Suppl.
1983:
305
92-9
-
High frequency mechanical ventilation in the treatment of neonatal respiratory distress.
Bland RD,
Sedin EG.
Int Anesthesiol Clin.
1983;
21
(3):
125-47
-
Neutrophil depletion does not prevent oxygen-induced lung injury in rabbits.
Raj JU,
Bland RD.
Chest.
1983;
83
(5 Suppl):
20S-21S
-
Vibratory ventilation decreases filtration of fluid in the lungs of newborn lambs.
Raj JU,
Goldberg RB, Bland RD.
Circ Res.
1983;
53
(4):
456-63
-
Edema formation in the newborn lung.
Bland RD,
Clin Perinatol.
1982;
9
(3):
593-611
-
Lung fluid balance in lambs before and after birth.
Bland RD,
Hansen TN, Haberkern CM, Bressack MA, Hazinski TA, Raj JU, Goldberg RB.
J Appl Physiol.
1982;
53
(4):
992-1004
-
Ontogeny and regulation of corticosteroid binding globulin capacity in plasma of fetal and newborn lambs.
Ballard PL,
Kitterman JA, Bland RD, Clyman RI, Gluckman PD, Platzker AC, Kaplan SL, Grumbach MM.
Endocrinology.
1982;
110
(2):
359-66
-
Studies of lung fluid balance in newborn lambs.
Bland RD,
Hansen TA, Hazinski TA, Haberkern CM, Bressack MA.
Ann N Y Acad Sci.
1982:
384
126-45
-
Vitamin E does not prevent oxygen-induced lung injury in newborn lambs.
Hansen TN,
Hazinski TA, Bland RD.
Pediatr Res.
1982;
16
(7):
583-7
-
Effect of hypercapnia on net filtration of fluid in the lungs of awake newborn lambs.
Haberkern CM,
Bland RD.
J Appl Physiol.
1981;
51
(2):
423-7
-
Intravenous infusion of tolazoline reduces pulmonary vascular resistance and net fluid filtration in the lungs of awake, hypoxic newborn lambs.
Bressack MA,
Bland RD.
Am Rev Respir Dis.
1981;
123
(2):
217-21
-
Alveolar hypoxia increases lung fluid filtration in unanesthetized newborn lambs.
Bressack MA,
Bland RD.
Circ Res.
1980;
46
(1):
111-6
-
Clearance of liquid from lungs of newborn rabbits.
Bland RD,
McMillan DD, Bressack MA, Dong L.
J Appl Physiol.
1980;
49
(2):
171-7
-
High frequency mechanical ventilation in severe hyaline membrane disease an alternative treatment?
Bland RD,
Kim MH, Light MJ, Woodson JL.
Crit Care Med.
1980;
8
(5):
275-80
-
Lung fluid balance in hypoxic, awake newborn lambs and mature sheep.
Bland RD,
Bressack MA, Haberkern CM, Hansen TN.
Biol Neonate.
1980;
38
(5-6):
221-8
-
Special considerations in oxygen therapy of infants and children.
Bland RD,
Am Rev Respir Dis.
1980;
122
(5 Pt 2):
45-54
-
Labor decreases the lung water content of newborn rabbits.
Bland RD,
Bressack MA, McMillan DD.
Am J Obstet Gynecol.
1979;
135
(3):
364-7
-
Lung fluid balance in awake newborn lambs with pulmonary edema from rapid intravenous infusion of isotonic saline.
Bland RD,
Bressack MA.
Pediatr Res.
1979;
13
(9):
1037-42
-
Pulmonary oxygen toxicity: increased microvascular permeability to protein in unanesthetized lambs.
Bressack MA,
McMillan DD, Bland RD.
Lymphology.
1979;
12
(3):
133-9
-
Decreased pulmonary transvascular fluid filtration in awake newborn lambs after intravenous furosemide.
Bland RD,
McMillan DD, Bressack MA.
J Clin Invest.
1978;
62
(3):
601-9
-
Effects of alveolar hypoxia on lung fluid and protein transport in unanesthetized sheep.
Bland RD,
Demling RH, Selinger SL, Staub NC.
Circ Res.
1977;
40
(3):
269-74
-
Lung fluid dynamics in awake newborn lambs.
Bland RD,
McMillan DD.
J Clin Invest.
1977;
60
(5):
1107-15
-
Movement of water and protein in the fetal and newborn lung.
Bland RD,
McMillan DD, Bressack MA.
Ann Rech Vet.
1977;
8
(4):
418-27
-
Pulmonary transvascular fluid filtration and microvascular permeability to plasma proteins in awake newborn lambs.
Bland RD,
McMillan DD.
Chest.
1977;
71
(2 suppl):
274
-
Rapid infusion of sodium bicarbonate and albumin into high-risk premature infants soon after birth: a controlled, prospective trial.
Bland RD,
Clarke TL, Harden LB.
Am J Obstet Gynecol.
1976;
124
(3):
263-7
-
Distribution volumes of [131I]albumin, [14C]sucrose, and 36Cl in sheep lung.
Selinger SL,
Bland RD, Demling RH, Staub NC.
J Appl Physiol.
1975;
39
(5):
773-9
-
Effect of acute hemorrhagic shock on pulmonary microvascular fluid filtration and protein permeability in sheep.
Demling RH,
Selinger SL, Bland RD, Staub NC.
Surgery.
1975;
77
(4):
512-9
-
Preparation of chronic lung lymph fistulas in sheep.
Staub NC,
Bland RD, Brigham KL, Demling R, Erdmann AJ, Woolverton WC.
J Surg Res.
1975;
19
(5):
315-20
-
Early albumin infusion to infants at risk for respiratory distress.
Bland RD,
Clarke TL, Harden LB, Meyer JL, Ries JP, Madden WA, Crast FW, Coyer WF, Bass JW.
Arch Dis Child.
1973;
48
(10):
800-5
-
Cord-blood total protein level as a screening aid for the idiopathic respiratory-distress syndrome.
Bland RD,
N Engl J Med.
1972;
287
(1):
9-13
-
Otitis media in the first six weeks of life: diagnosis, bacteriology, and management.
Bland RD,
Pediatrics.
1972;
49
(2):
187-97
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