Steven Artandi

Publications

• Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling. Shkreli M, Sarin KY, Pech MF, Papeta N, Chang W, Brockman SA, Cheung P, Lee E, Kuhnert F, Olson JL, Kuo CJ, Gharavi AG, D'Agati VD, Artandi SE. Nat Med. 2012; 18 (1): 111-9
• TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends. Zhong FL, Batista LF, Freund A, Pech MF, Venteicher AS, Artandi SE. Cell. 2012; 150 (3): 481-94
• Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita. Zhong F, Savage SA, Shkreli M, Giri N, Jessop L, Myers T, Chen R, Alter BP, Artandi SE. Genes Dev. 2011; 25 (1): 11-6
• Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Chu C, Qu K, Zhong FL, Artandi SE, Chang HY. Mol Cell. 2011; 44 (4): 667-78
• In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. Stem Cells. 2011; 29 (11): 1717-26
• TRAPping telomerase within the intestinal stem cell niche. Pech MF, Artandi SE. EMBO J. 2011; 30 (6): 986-7
• Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE. Nature. 2011; 474 (7351): 399-402
• Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. Sacco A, Mourkioti F, Tran R, Choi J, Llewellyn M, Kraft P, Shkreli M, Delp S, Pomerantz JH, Artandi SE, Blau HM. Cell. 2010; 143 (7): 1059-71
• Telomeres and telomerase in cancer. Artandi SE, DePinho RA. Carcinogenesis. 2010; 31 (1): 9-18
• A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE. Science. 2009; 323 (5914): 644-8
• Reverse transcribing the code for chromosome stability. Artandi SE, Cooper JP. Mol Cell. 2009; 36 (5): 715-9
• Stem cell aging and aberrant differentiation within the niche. Choi J, Artandi S. Cell Stem Cell. 2009; 5 (1): 6-8
• TCAB1: driving telomerase to Cajal bodies. Venteicher AS, Artandi SE. Cell Cycle. 2009; 8 (9): 1329-31
• Telomerase modulates Wnt signalling by association with target gene chromatin. Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE. Nature. 2009; 460 (7251): 66-72
• Telomere uncapping, chromosomes, and carcinomas. Batista LF, Artandi SE. Cancer Cell. 2009; 15 (6): 455-7
• Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Venteicher AS, Meng Z, Mason PJ, Veenstra TD, Artandi SE. Cell. 2008; 132 (6): 945-57
• Aging, graying and loss of melanocyte stem cells. Sarin KY, Artandi SE. Stem Cell Rev. 2007; 3 (3): 212-7
• DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse. Maser RS, Wong KK, Sahin E, Xia H, Naylor M, Hedberg HM, Artandi SE, DePinho RA. Mol Cell Biol. 2007; 27 (6): 2253-65
• Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo. Rajaraman S, Choi J, Cheung P, Beaudry V, Moore H, Artandi SE. Proc Natl Acad Sci U S A. 2007; 104 (45): 17747-52
• Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain. Middleman EJ, Choi J, Venteicher AS, Cheung P, Artandi SE. Mol Cell Biol. 2006; 26 (6): 2146-59
• Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene. Artandi SE, J Exp Med. 2006; 203 (5): 1143-5
• Telomeres, telomerase, and human disease. Artandi SE, N Engl J Med. 2006; 355 (12): 1195-7
• Conditional telomerase induction causes proliferation of hair follicle stem cells. Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE. Nature. 2005; 436 (7053): 1048-52
• Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. Artandi SE, Attardi LD. Biochem Biophys Res Commun. 2005; 331 (3): 881-90
• Complex roles for telomeres and telomerase in breast carcinogenesis. Artandi SE, Breast Cancer Res. 2003; 5 (1): 37-41
• Constitutive telomerase expression promotes mammary carcinomas in aging mice. Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Horner JW, Weiler SR, Carrasco RD, DePinho RA. Proc Natl Acad Sci U S A. 2002; 99 (12): 8191-6
• Telomere shortening and cell fates in mouse models of neoplasia. Artandi SE, Trends Mol Med. 2002; 8 (1): 44-7
• A critical role for telomeres in suppressing and facilitating carcinogenesis. Artandi SE, DePinho RA. Curr Opin Genet Dev. 2000; 10 (1): 39-46
• Mice without telomerase: what can they teach us about human cancer? Artandi SE, DePinho RA. Nat Med. 2000; 6 (8): 852-5
• Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Nature. 2000; 406 (6796): 641-5
• p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA. Cell. 1999; 97 (4): 527-38