Richard J. Reimer, MD

Publications

• Biochemistry to the rescue: a ClC-2 auxiliary subunit provides a tangible link to leukodystrophy. Maduke MC, Reimer RJ. Neuron. 2012; 73 (5): 855-7
• Glutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformation. Dulla CG, Tani H, Brill J, Reimer RJ, Huguenard JR. Neurobiol Dis. 2012: 49C 232-246
• Glutamine is required for persistent epileptiform activity in the disinhibited neocortical brain slice. Tani H, Dulla CG, Huguenard JR, Reimer RJ. J Neurosci. 2010; 30 (4): 1288-300
• Structure-function studies of the SLC17 transporter sialin identify crucial residues and substrate-induced conformational changes. Courville P, Quick M, Reimer RJ. J Biol Chem. 2010; 285 (25): 19316-23
• Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport. Zaia KA, Reimer RJ. J Biol Chem. 2009; 284 (13): 8439-48
• The lysosomal sialic acid transporter sialin is required for normal CNS myelination. Prolo LM, Vogel H, Reimer RJ. J Neurosci. 2009; 29 (49): 15355-65
• Imaging of glutamate in brain slices using FRET sensors. Dulla C, Tani H, Okumoto S, Frommer WB, Reimer RJ, Huguenard JR. J Neurosci Methods. 2008; 168 (2): 306-19
• G328E and G409E sialin missense mutations similarly impair transport activity, but differentially affect trafficking. Myall NJ, Wreden CC, Wlizla M, Reimer RJ. Mol Genet Metab. 2007; 92 (4): 371-4
• Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy. Tani H, Bandrowski AE, Parada I, Wynn M, Huguenard JR, Prince DA, Reimer RJ. Neurobiol Dis. 2007; 25 (2): 230-8
• Biochemical and genetic analysis of ANK in arthritis and bone disease. Gurley KA, Reimer RJ, Kingsley DM. Am J Hum Genet. 2006; 79 (6): 1017-29
• Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Okumoto S, Looger LL, Micheva KD, Reimer RJ, Smith SJ, Frommer WB. Proc Natl Acad Sci U S A. 2005; 102 (24): 8740-5
• Varied mechanisms underlie the free sialic acid storage disorders. Wreden CC, Wlizla M, Reimer RJ. J Biol Chem. 2005; 280 (2): 1408-16
• Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Reimer RJ, Edwards RH. Pflugers Arch. 2004; 447 (5): 629-35