Kathleen M. Sakamoto

Publications

• CREB and leukemogenesis. Cho EC, Mitton B, Sakamoto KM. Crit Rev Oncog. 2011; 16 (1-2): 37-46
• The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway. Hernandez-Davies JE, Zape JP, Landaw EM, Tan X, Presnell A, Griffith D, Heinrich MC, Glaser KB, Sakamoto KM. Mol Cancer Ther. 2011; 10 (6): 949-59
• Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Danilova N, Sakamoto KM, Lin S. Blood. 2008; 112 (13): 5228-37
• The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Shankar DB, Cheng JC, Kinjo K, Federman N, Moore TB, Gill A, Rao NP, Landaw EM, Sakamoto KM. Cancer Cell. 2005; 7 (4): 351-62
• Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain. Verma R, Peters NR, D'Onofrio M, Tochtrop GP, Sakamoto KM, Varadan R, Zhang M, Coffino P, Fushman D, Deshaies RJ, King RW. Science. 2004; 306 (5693): 117-20
• Development of Protacs to target cancer-promoting proteins for ubiquitination and degradation. Sakamoto KM, Kim KB, Verma R, Ransick A, Stein B, Crews CM, Deshaies RJ. Mol Cell Proteomics. 2003; 2 (12): 1350-8
• Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. Shou W, Sakamoto KM, Keener J, Morimoto KW, Traverso EE, Azzam R, Hoppe GJ, Feldman RM, DeModena J, Moazed D, Charbonneau H, Nomura M, Deshaies RJ. Mol Cell. 2001; 8 (1): 45-55
• Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation. Sakamoto KM, Kim KB, Kumagai A, Mercurio F, Crews CM, Deshaies RJ. Proc Natl Acad Sci U S A. 2001; 98 (15): 8554-9
• Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia. Chang VY, Basso G, Sakamoto KM, Nelson SF. BMC Cancer. 2013: 13 55
• Increased abscess formation and defective chemokine regulation in CREB transgenic mice. Wen AY, Landaw EM, Ochoa R, Cho M, Chao A, Lawson G, Sakamoto KM. PLoS One. 2013; 8 (2): e55866
• MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation. Pigazzi M, Manara E, Bresolin S, Tregnago C, Beghin A, Baron E, Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G. Haematologica. 2013; 98 (4): 602-10
• Sox4 cooperates with CREB in myeloid transformation. Sandoval S, Kraus C, Cho EC, Cho M, Bies J, Manara E, Accordi B, Landaw EM, Wolff L, Pigazzi M, Sakamoto KM. Blood. 2012; 120 (1): 155-65
• The neutropenic diet... still ageless? Aftandilian CC, Milotich C, Sakamoto KM. Oncology (Williston Park). 2012; 26 (6): 586, 588-9
• Increasing diversity in pediatric hematology/oncology. Frugé E, Lakoski JM, Luban N, Lipton JM, Poplack DG, Hagey A, Felgenhauer J, Hilden J, Margolin J, Vaiselbuh SR, Sakamoto KM. Pediatr Blood Cancer. 2011; 57 (1): 147-52
• The role of HDAC6 in cancer. Aldana-Masangkay GI, Sakamoto KM. J Biomed Biotechnol. 2011: 2011 875824
• Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM. Leuk Lymphoma. 2011; 52 (8): 1544-55
• Targeting CREB for cancer therapy: friend or foe. Xiao X, Li BX, Mitton B, Ikeda A, Sakamoto KM. Curr Cancer Drug Targets. 2010; 10 (4): 384-91
• CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, Schmid I, Shankar DB, Kasahara N, Stripecke R, Bhatia R, Landaw EM, Sakamoto KM. Blood. 2008; 111 (3): 1182-92
• Expression profile of CREB knockdown in myeloid leukemia cells. Pellegrini M, Cheng JC, Voutila J, Judelson D, Taylor J, Nelson SF, Sakamoto KM. BMC Cancer. 2008: 8 264
• Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer. Rodriguez-Gonzalez A, Cyrus K, Salcius M, Kim K, Crews CM, Deshaies RJ, Sakamoto KM. Oncogene. 2008; 27 (57): 7201-11
• Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia. Crans-Vargas HN, Landaw EM, Bhatia S, Sandusky G, Moore TB, Sakamoto KM. Blood. 2002; 99 (7): 2617-9