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Euan A. Ashley

Academic Appointments

  • Associate Professor of Medicine (Cardiovascular), of Genetics and, by courtesy, of Pathology at the Stanford University Medical Center

Key Documents

Contact Information

  • Clinical Offices
    Cardiovascular Medicine 300 Pasteur Dr A265 MC 5319 Stanford, CA 94305
    Tel Work (650) 736-7878 Fax (650) 498-7452
  • Academic Offices
    Alternate Contact
    Terra Coakley Program Manager, Center for Inherited Cardiovascular Disease Tel Work 650 498 4900
    Not for medical emergencies or patient use

Professional Overview

Bio

Born and raised in Scotland, Euan Angus Ashley graduated with 1st class Honors in Physiology and Medicine from the University of Glasgow. He completed medical residency and a PhD in molecular cardiology at the University of Oxford before moving to Stanford University where he trained in cardiology and advanced heart failure joining the faculty in 2006. His group is focused on the application of genomics to medicine. In 2010, he led the team that carried out the first clinical interpretation of a human genome. The paper published in the Lancet was the focus of over 300 news stories, became one of the most cited articles in clinical medicine that year, and is currently featured in the Genome Exhibition at the Smithsonian in DC. The team extended the approach in 2011 to a family of four and now routinely apply genome sequencing to the diagnosis of patients at Stanford hospital where Dr Ashley directs the Clinical Genome Service and the Center for Inherited Cardiovascular Disease. In 2013, Dr Ashley was recognized at the White House Data to Knowledge to Action event for his contributions to Personalized Medicine. Dr Ashley is a recipient of the National Innovation Award from the American Heart Association (AHA) and a National Institutes of Health (NIH) Director’s New Innovator Award. He is a member of the AHA Council on Functional Genomics, and the Institute of Medicine (IOM) of the National Academy of Sciences Roundtable on Translating Genomic-Based Research for Health. He is a peer reviewer for the NIH and the AHA as well as journals including Nature, the New England Journal of Medicine, the Lancet and the Journal of Clinical Investigation. He is co-founder of Personalis, Inc, a Menlo Park based genetic diagnostics company.

Father to three young Americans, in his ‘spare’ time, he tries to understand American football, plays the saxophone, and conducts research on the health benefits of single malt Scotch whisky.

Clinical Focus

  • Cardiology
  • Inherited cardiovascular disease
  • Heart Failure
  • Genomic medicine
  • Hypertrophic Cardiomyopathy
  • Cardiomyopathy, Dilated
View All 7clinical focus of Euan Ashley

Academic Appointments

Administrative Appointments

  • Co-Director, Clinical Genomics Service (2013 - present)
  • Director, Stanford Center for Inherited Cardiovascular Disease (2010 - present)
  • Co-Director, Stanford Research Training Program in Myocardial Biology (2010 - present)
  • Member, Institute of Medicine Roundtable on Translating Genomic-based Research for Health (2012 - present)
  • Leadership committee, AHA Council on Functional Genomics and Translational Biology (2009 - present)
  • Director, Stanford Cardiopulmonary Exercise Testing Laboratory (2007 - present)
View All 9administrative appointments of Euan Ashley

Honors and Awards

  • NIH Director's New Innovator Award, National Institutes of Health (2009)
  • Innovative Research Award, American Heart Association (2008)
  • Faculty Scholar, Donald E. and Delia B. Baxter Foundation (2009)
  • Career Development Award (K08), National Institutes of Health (2006)
  • Western Affiliates Young Investigator Award, American Heart Association (2004)
  • Cardiovascular Medicine Basic Science Award, Stanford University (2004)
View All 9honors and awards of Euan Ashley

Professional Education

Internship: University of Glasgow, Scotland (1997)
Medical Education: University of Glasgow, Scotland (1996)
Residency: University of Oxford, UK (1999)
Fellowship: University of Oxford, UK (2002)
Fellowship: Stanford University Medical Center CA (2006)
DPhil: University of Oxford, Molecular Cardiology (2002)
View All 9

Community and International Work

Courses

2013-14

Postdoctoral Advisees

Ayca ErbilginYoung Min Kim

Graduate and Fellowship Program Affiliations

Scientific Focus

Current Research and Scholarly Interests

The Ashley lab is focused on the application of genomics to medicine. We develop methods for the interpretation of whole genome sequencing data to improve diagnosis of genetic disease and to personalize the practice of medicine. We love big data questions and are obsessed with systems approaches to biology especially analysis of network graphs. The wet bench is where we test causality of key genes and investigate the biology of network modules. It is also the focus of our translational efforts. Therapeutic development is a near term goal and several of our discoveries are the focus of patents or are being actively pursued by pharmaceutical and biotechnology partners.

Publications

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Publication Topics

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