Clinical Focus

• Neurology
• Glioma
• glioblastoma
• Brain Metastasis
• Carcinomatosis, Leptomeningeal

Professional Education

Current Research Interests

Glioblastoma is an aggressive brain cancer with limited options for therapy. Currently, our group is looking to bring at least 2 new trials for treatment at the time of diagnosis and at recurrence to Stanford.

The spread of systemic cancer, like lung and breast cancers, to the covering of the brain, is adevastating and often lethal complication. I am working to bring a trials for early detection and treatment to Stanford, with the and making this a unique focus of our new brain tumor center.

Clinical Trials

• Phase II Rindopepimut/GM-CSF in Relapsed EGFRvIII-Positive Glioblastoma Recruiting
• A Study of MEDI-575 in Subjects With Recurrent Glioblastoma Multiforme No longer recruiting

Publications

• The Role of BCNU Polymer Wafers (Gliadel) in the Treatment of Malignant Glioma. Nagpal S, Neurosurg Clin N Am. 2012; 23 (2): 289-295
• Bevacizumab improves quality of life in patients with recurrent glioblastoma. Nagpal S, Harsh G, Recht L. Chemother Res Pract. 2011: 2011 602812
• Treatment and prophylaxis of hematologic malignancy in the central nervous system. Nagpal S, Recht L. Curr Treat Options Neurol. 2011; 13 (4): 400-12
• Cardiac rupture after intravenous t-PA administration in acute ischemic stroke. Dhand A, Nakagawa K, Nagpal S, Gelfand JM, Kim AS, Smith WS, Tihan T. Neurocrit Care. 2010; 13 (2): 261-2
• Treatment and prevention of secondary CNS lymphoma. Nagpal S, Glantz MJ, Recht L. Semin Neurol. 2010; 30 (3): 263-72