Hanlee P. Ji
Academic Appointments
- Assistant Professor, Medicine - Oncology
- Member, Stanford Cancer Institute
Key Documents
Contact Information
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Clinical Offices
Medical Oncology 875 Blake Wilbur Dr Clinic B MC 5820 Stanford, CA 94305 Tel Work (650) 498-6000 Fax (650) 736-4167
- Academic Offices
Alternate Contact Donna Galvez Administration Ji Research Group Email Tel Work 650-721-1503Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Cancer> GI Oncology
- Medical Oncology
- Oncology (Cancer)
- Gastrointestinal Neoplasms
- Inherited Cancer Disorders
Administrative Appointments
- Senior Associate Director, Stanford Genome Technology Center (2008 - present)
Honors and Awards
- Research Scholar Award, American Cancer Society (2013)
- Clinical Scientist Development Award, Doris Duke Charitable Foundation (2009)
- Physician Scientist Early Career Award, Howard Hughes Medical Institute (2008)
- Merit Award for Research Achievement, American Society Clinical Oncology Foundation (2006)
- American Association Cancer Research, Scholar-in-Training Award for Research Achievement (2005)
- Physician-Scientist Fellowship Award, Howard Hughes Medical Institute (1998)
Professional Education
| Fellowship: | Stanford University Hospital - Internal Medicine CA (2005) |
| Board Certification: | Medical Oncology, American Board of Internal Medicine (2004) |
| Residency: | University of Washington WA (2001) |
| Residency: | University Of Iowa Hospitals & Clinics IA (1996) |
| Medical Education: | John Hopkins University School of Medicine MD (1994) |
| B.A.: | Reed College, Biology |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
To improve the lives of individuals with cancer, our research group has embarked on a research initiative to use cutting edge genetics and technology to interrogate the fundamental genetic" digital" code responsible for cancer development and overall clinical behavior.
We are pursuing projects focused on personalized medicine. Specifically, we are interested in using genetic and genomic approaches in oncology to improve targeted cancer therapy development, make accurate prognosis, prediction of cancer therapy efficacy and identify clinically relevant cancer mutations. These projects are aimed towards establishing the paradigm for individualized medicine, facilitate the introduction of these approaches into validation clinical studies and thus develop the next generation of cancer diagnostics and treatment.
Our research program is specifically focused on:
1) Discovery and validation of genetic signatures portending prognosis and therapeutic drug targets for individuals with cancer
2) Development of novel approaches for analyzing cancer genomes and identifying personalized therapeutic targets
3) Determining inherited pathogenic mutations that increase the risk of developing gastrointestinal malignancies
4) The genetic analysis of complete cancer genome sequences derived from inherited cancer
5) Technology development on novel genetic diagnostic methods to help individuals with cancer
Clinical Trials
- Recruiting Phase II Gemcitabine + Fractionated Stereotactic Radiotherapy for Unresectable Pancreatic Adenocarcinoma
- Recruiting Molecular Analysis of Thoracic Malignancies
- Recruiting Genome, Proteome and Tissue Microarray in Childhood Acute Leukemia
- Recruiting Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples
- Recruiting Molecular Genetic and Pathological Studies of Anal Tumors
Publications
- A cross-sample statistical model for SNP detection in short-read sequencing data. Nucleic Acids Res. 2012; (1): e5
- Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype. Biodiscovery. 2012; (1)
- Improving bioinformatic pipelines for exome variant calling. Genome Med. 2012; (1): 7
- Quantitative and Sensitive Detection of Cancer Genome Amplifications from Formalin Fixed Paraffin Embedded Tumors with Droplet Digital PCR. Transl Med (Sunnyvale). 2012; (2)
- The Human OligoGenome Resource: a database of oligonucleotide capture probes for resequencing target regions across the human genome. Nucleic Acids Res. 2012; (Database issue): D1137-43
- Ultrasensitive detection of rare mutations using next-generation targeted resequencing. Nucleic Acids Res. 2012; (1): e2
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