George Triadafilopoulos
Academic Appointments
- Clinical Professor, Medicine - Gastroenterology & Hepatology
Key Documents
Contact Information
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Clinical Offices
El Camino GI Medicine Associates 2490 Hospital Dr Ste 211 Mountain View, CA 94040 Tel Work (650) 988-7488 Fax (650) 988-7486
- Academic Offices
Personal Information Email Tel (650) 988-7488Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Gastroenterology
Honors and Awards
- Distinguished Service Award, American Society for Gastrointestinal Endoscopy (2009)
Professional Education
| Residency: | Wayne State University School of Medicine MI (1982) |
| Board Certification: | Gastroenterology, American Board of Internal Medicine (1985) |
| Fellowship: | Boston University School Of Medicine MA (1985) |
| Board Certification: | Internal Medicine, American Board of Internal Medicine (1983) |
| Residency: | Sinai Hospital - Detroit MI (1983) |
| Medical Education: | Aristotle University of Thessaloniki, Greece (1979) |
Graduate & Fellowship Program Affiliations
Scientific Focus
Current Research Interests
My primary research interest concerns factors involved in the pathogenesis of gastro-esophageal reflux disease (GERD) and its complications, such as Barrett's esophagus. Over the past decade I have explored the potential role of COX-2 expression and activity, prostaglandin and leukotriene production and cell proliferation in inducing and amplifying symptoms and disease evolution. Ongoing studies in the area of Barrett's metaplasia involve characterizing unique cell surface or intracellular molecular changes that occur in the early stages of metaplastic transformation and identification of environmental factors that predispose to esophageal metaplasia. In particular, I am interested in the role of acid and bile reflux in modifying cellular alterations and contributing to dysplasia and neoplasia. Furthermore, in clinical studies, I am investigating the role of 24-hour dual pH monitoring in the management of patients with reflux-like dyspepsia, esophagitis, and BarrettÂ’s esophagus, and particularly the role of intensive proton pump inhibitor therapy in chemoprevention against esophageal adenocarcinoma. I have a very active clinical base of patients with BarrettÂ’s esophagus in which advanced diagnostic (narrow band imaging, in vivo confocal microscopy, chromo-endoscopy) as well as therapeutic (endoscopic mucosal resection, radiofrequency ablation) modalities are prospectively explored and validated.
Publications
- Hepatic Abscess with Biliary Communication Following Transarterial Chemoembolization of Hepatocellular Carcinoma. Dig Dis Sci. 2013
- Holiday pains: a case of radiation-induced mesenteric ischemia. Dig Dis Sci. 2013; (2): 349-53
- Indications and safety of proton pump inhibitor drug use in patients with cancer. Expert Opin Drug Saf. 2013
- Update on foreign bodies in the esophagus: diagnosis and management. Curr Gastroenterol Rep. 2013; (4): 317
- Abdominal mass, anemia, diabetes mellitus, and necrolytic migratory erythema. Dig Dis Sci. 2012; (6): 1465-8
- Acute fulminant hepatic failure associated with parvovirus B19 infection in an immunocompetent adult. Dig Dis Sci. 2012; (11): 2811-3
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