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Boris Heifets

Academic Appointments

Key Documents

Contact Information

Professional Overview

Clinical Focus

  • Anesthesia

Academic Appointments

Honors and Awards

  • Mentored Research Training Grant - Basic Science, Foundation for Anesthesia Education and Research (2013-2015)
  • Oustanding Contributions to Anesthesia Research, Department of Anesthesiology, Pain & Perioperative Medicine (2013)
  • Internal Grant Program Award, Department of Anesthesiology, Pain & Perioperative Medicine (2012)

Professional Education

Residency: Stanford University School of Medicine CA (2013)
Internship: Memorial Sloan-Kettering Cancer Center NY (2010)
Fellowship: Stanford Hospital & Clinics, Research (2013)
Medical Education: Albert Einstein College of Medicine NY (2009)
PhD: Albert Einstein College of Medicine, Neuroscience (2009)
BS: Yale University, Psychobiology/Neuroscience (1999)

Scientific Focus

Current Research and Scholarly Interests

Neurosurgery for intractable neuropsychiatric illness has emerged as a safe and effective treatment option for many patients, most notably those with Parkinson’s Disease (PD). Deep Brain Stimulation (DBS) reduces PD patients’ symptoms and drug-related side effects. Advances in the nascent field of optogenetics have led to the discovery of a neural circuit crucial for producing the therapeutic response to DBS, centered on cortical afferents to the subthalamic nucleus (STN). We hypothesize that selective, long lasting modification of synapses within this circuit will improve efficacy of DBS. We describe a method to selectively study the synapses of neural pathways underlying DBS’ therapeutic effect, using transgenic mice whose PD-like symptoms are reversed by optical stimulation. We are currently developing neuroactive compounds that could be developed as intraoperative therapeutic adjuncts to existing or modified DBS protocols.

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