Translational Medicine

As a leader in the global scientific and medical community, Stanford Medicine continues to pioneer new approaches to understanding and treating melanoma. With a better grasp of how and why normal melanocytes become melanoma, more effective therapies are now possible.

By drawing upon discoveries made in the basic sciences: biochemistry, immunology, engineering and physics, we are "translating" these advances into changes in the management of melanoma. This collaboration between basic scientists and clinician investigators forges a bridge between the scientific research bench to the patient's bedside.

Translational Medicine/Laboratory Correlate Studies (involves blood or tissue collection from melanoma patients)

Study Title

Principal Investigator

Characterization of Tumor-Specific T Cells in Melanoma and in Healthy and Vitiligo Controls; Cancer-induced Immune Dysfunction in Melanoma; Biology of Tumor Infiltrating Lymphocytes: Analysis and Manipulation of T cell Response to Cancer

Peter Lee, MD, PhD

Tumor Infiltrating Immune Responses in Cancer Patients; T-cell Functionality and Anti-melanoma Immune Responses

Mark Davis, MD

Prospective Isolation of the Cancer Stem Cell in Melanoma Patients

Irving Weissman, MD

Susceptibility to Skin Cancer: Assessment of Abnormal Transcriptional Response in Melanoma Patients

Gilbert Chu, MD

Genetic Alterations Related to Induction of Melanocytic Neoplasia in Human Tissue

Paul Khavari, MD, PhD

Multi-gene Approach to Improve the Diagnosis and Prognosis of Cutaneous Melanoma; Role of Tumor Lymphangiogenesis in Predicting Nodal and Systemic Metastasis in Patients with Primary Cutaneous Melanoma

Soheil Dadras, MD, PhD

Creation of a Melanocytic Tumor Tissue Microarray for Studies Comparing Potential Diagnostic, Prognostic, and Therapeutic-related Markers in Benign versus Malignant Melanocytic Neoplasms David Cassarino, MD, PhD

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