Stanford Cardiac Arrhythmia Service

Intracardiac CryoAblation for AVNRT

Contact Information

If you are interested or have questions regarding this trial, please contact the Stanford Cardiac Electrophysiology and Arrhythmia group:

(650) 723-7111

Principal Investigator:
Paul J. Wang, MD

Study Coordinator:
Linda Norton, RN, MSN

Research Coordinator:
Sneha Bhamre, MPH

Supraventricular Tachycardia (SVT) – is an arrhythmia that occurs above the ventricles. The most common type of SVT is called A-V nodal Reentry Tachycardia, (AVNRT) which accounts for 50% of cases.  In AVNRT, the electrical impulse travels in and around the A-V node. The electrical signal may circle continuously around and around this pathway, causing the tachycardia to continue.

Catheter ablation is a technique that serves as an alternative for medications for supraventricular tachycardia. There are two energy sources that are commonly used for the catheter ablation of SVT’s.  These include catheters that perform cryoablation (sub zero temperatures) and the use of radiofrequency energy (thermal energy) for ablation.

An ablation for AVNRT targets a region of heart cells outside the A-V node proper to return the heart rate to a normal rhythm.

Study Purpose

Additional Resources

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Stanford Clinical Trials

Medtronic, Inc. is sponsoring a clinical study assessing the safety and efficacy of the Freezor Xtra CryoAblation Catheter for cryoablation of the conducting tissue of the heart for patients with AVNRT.

The Freezor CryoAblation Catheter and Console have been approved for the minimally invasive surgical treatment of SVT.

The purpose of this study is to give evidence to support the use of this catheter system for use in patients with AVNRT using an endocardial approach without surgery.

Required visits post-procedure will occur at 1, 3, and 6 months with phone follow-up at 1, 2, and 3 years. Compensation for the 3 and 6 month visits will be provided by the sponsor; additionally, the sponsor will compensate travel costs for all visits.

It is important to know that the treatment procedures for this arrhythmia will be similar regardless of whether a patient chooses to participate in this study and that involvement is completely optional.

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